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Ex Vivo Infection of Human Lymphoid Tissue and Female Genital Mucosa with Human Immunodeficiency Virus 1 and Histoculture
Published on: October 12, 2018
Nodulo-ulcerative and erythrodermic secondary syphilis in human immunodeficiency virus-infected individuals
Swagata Tambe1, Uddhao Zambare1, Chitra Nayak1
1Department of Dermatology, Topiwala National Medical College & BYL Nair Charitable Hospital, Mumbai, India.
Abstract:
Syphilis and human immunodeficiency virus (HIV) infections are both transmitted sexually. Co-infection of HIV and syphilis alters the course of both diseases. Clinical presentation of syphilis in patients of HIV may be atypical. HIV-infected individuals are at risk of developing lues maligna, which is characterized by nodulo-ulcerative lesions associated with severe constitutional symptoms. Erythroderma secondary to generalized papulo-squamous lesions of secondary syphilis is also uncommon. Here we report two cases of atypical presentations of secondary syphilis in HIV-positive patients.
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