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A Rodent Model of The Ross Operation: Syngeneic Pulmonary Artery Graft Implantation in A Systemic Position
Published on: April 1, 2022
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Technical Varieties of Ross Procedure: A Case Series
Huma Fatima1, Muneer Amanullah2, Asif Hasan Siddiqui2
1Medical Student, The Aga Khan University Hospital, Karachi, Pakistan.
Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
|January 12, 2019
Summary
The Ross procedure, using pulmonary autografts, shows excellent outcomes in younger adults, avoiding anticoagulation and re-intervention. This study highlights its durability and safety for aortic valve replacement.
Area of Science:
- Cardiovascular Surgery
- Pediatric Cardiology
- Thoracic Surgery
Background:
- The Ross procedure utilizes the pulmonary autograft for aortic valve replacement, offering growth potential and avoiding anticoagulation, particularly beneficial for pediatric patients.
- Aortic regurgitation was the primary indication for surgery in this cohort.
Purpose of the Study:
- To report the postoperative outcomes of two technical variations of the Ross procedure.
- To evaluate the long-term efficacy and safety of the Ross procedure in adult patients.
Main Methods:
- A case series of eight patients undergoing the Ross procedure between January 2007 and December 2016.
- Two techniques were used: free-standing root replacement (n=6) and modified root replacement with Dacron graft stabilization (n=2).
- Right ventricular outflow tract reconstruction involved either a Contegra bioprosthesis (n=4) or a manually constructed valved conduit (n=4).
Main Results:
- No mortality or re-intervention was observed in the study cohort.
- Both technical variations of the Ross procedure demonstrated favorable outcomes.
- Patients experienced freedom from anticoagulation and right ventricular outflow tract conduit failure.
Conclusions:
- Technical variations of the Ross procedure are safe and effective for aortic valve replacement in younger adults.
- The procedure offers a durable solution without the need for long-term anticoagulation.
- Excellent postoperative outcomes suggest the Ross procedure is a viable option for selected patients.
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