Related Experiment Video
Updated: Jan 30, 2026

Metagenomic Analysis of Silage
Published on: January 13, 2017
Identifying accurate metagenome and amplicon software via a meta-analysis of sequence to taxonomy benchmarking
Paul P Gardner1,2, Renee J Watson1, Xochitl C Morgan3
1Biomolecular Interactions Centre, School of Biological Sciences, University of Canterbury, Christchurch, New Zealand.
Abstract:
Metagenomic and meta-barcode DNA sequencing has rapidly become a widely-used technique for investigating a range of questions, particularly related to health and environmental monitoring. There has also been a proliferation of bioinformatic tools for analysing metagenomic and amplicon datasets, which makes selecting adequate tools a significant challenge. A number of benchmark studies have been undertaken; however, these can present conflicting results. In order to address this issue we have applied a robust Z-score ranking procedure and a network meta-analysis method to identify software tools that are consistently accurate for mapping DNA sequences to taxonomic hierarchies. Based upon these results we have identified some tools and computational strategies that produce robust predictions.
Related Concept Videos
Taxonomy
Hierarchy of Taxonomy
The hierarchy that Carolus Linnaeus first...
Modern Molecular Taxonomy
Statistical Software for Data Analysis and Clinical Trials
Applications of Molecular Taxonomy
Directing Effect of Substituents: meta-Directing Groups
Nursing Interventions I: Taxonomy of Nursing Interventions
A nursing intervention is a treatment or action based on scientific concepts and knowledge from the nursing, behavioral, and physical sciences. Identifying and prioritizing nursing interventions based on the desired outcome...

