Related Experiment Video
Updated: Jan 30, 2026
05:24
Multifractal Spectrum Analysis for Assessing Pulmonary Nodule Malignancy
Published on: January 10, 2025
882
Comparison between the application of microcoil and hookwire for localizing pulmonary nodules
Libao Hu1, Jian Gao2, Chen Chen1
1Department of Radiology, Peking University People's Hospital, No. 11 Xizhimen South Avenue, Beijing, China.
European Radiology
|January 12, 2019
Summary
Microcoil and hookwire localization of small pulmonary nodules are equally effective for surgery. Microcoil use resulted in fewer complications, despite more complex deployment, making it a safer option for lung nodule localization.
Area of Science:
- Pulmonology
- Thoracic Surgery
- Medical Imaging
Background:
- Small pulmonary nodules require precise localization for successful surgical resection.
- Computed tomography (CT)-guided percutaneous localization is a common method for guiding thoracic surgery.
- Microcoils and hookwires are two techniques used for CT-guided localization.
Purpose of the Study:
- To compare the efficacy and safety of microcoil versus hookwire localization for small pulmonary nodules.
- To evaluate localization success rates and complication incidence.
- To determine the optimal method for preoperative localization of pulmonary nodules.
Main Methods:
- A retrospective, non-randomized cohort study of 112 patients undergoing CT-guided percutaneous localization.
- Comparison of a microcoil group (79 patients) and a hookwire group (33 patients).
- Analysis of localization success rates, pneumothorax, chest pain, and overall complications.
Main Results:
- Localization success rates were similar: 94.9% for microcoils and 93.9% for hookwires (p=0.836).
- The hookwire group showed increased rates of pneumothorax (p=0.000) and moderate to severe chest pain (p=0.027).
- Microcoil localization was associated with fewer overall complications compared to hookwire localization.
Conclusions:
- Both microcoil and hookwire methods are effective for localizing small pulmonary nodules prior to video-assisted thoracoscopic surgery (VATS).
- Microcoil localization offers a safer alternative due to a lower incidence of complications.
- While microcoil deployment is more complex, the reduced complication rate favors its use.
Related Concept Videos
01:23Local Anesthetics: Common Agents and Their Applications
964
Local anesthetics (LAs) are commonly used for various applications in medical and dental procedures. Some of the common agents used are cocaine, lidocaine, and bupivacaine.
Cocaine is an ester of benzoic acid and methylecgogine. It is used to anesthetize and vasoconstrict locally. Currently, it is used primarily for topical applications. It is beneficial for surgeries on the upper respiratory tract, providing anesthesia and shrinking the mucosa. Cocaine in the form of cocaine hydrochloride is...
Cocaine is an ester of benzoic acid and methylecgogine. It is used to anesthetize and vasoconstrict locally. Currently, it is used primarily for topical applications. It is beneficial for surgeries on the upper respiratory tract, providing anesthesia and shrinking the mucosa. Cocaine in the form of cocaine hydrochloride is...
964
01:11Local Anesthetics: Clinical Application as Spinal Anesthesia
1.4K
Spinal anesthetics are given during lower abdomen and limb surgeries to block sensory and motor neurons. They are administered in the mid to low lumbar regions, primarily acting on the cauda equina's nerve roots. The blockade level depends on the local anesthetic (LA) concentration. Usually, low LA concentrations are sufficient to block sensory fibers, while only high LA concentrations block motor fibers. Other factors like injection volume and speed, the patient's posture, and the drug...
1.4K
01:29Local Anesthetics: Clinical Application as Epidural Anesthesia
735
Epidural anesthetics are administered in the fat-filled epidural space, the outermost part of the spinal canal. This technique is commonly employed for pain management and anesthesia during lower abdomen and pelvis surgeries or labor and delivery.
Since epidural anesthetics can be infused through an epidural catheter, all types of drugs, including short-acting ones, can be administered. Chloroprocaine and lidocaine are examples of short and long-duration anesthetics, respectively. Bupivacaine...
Since epidural anesthetics can be infused through an epidural catheter, all types of drugs, including short-acting ones, can be administered. Chloroprocaine and lidocaine are examples of short and long-duration anesthetics, respectively. Bupivacaine...
735
02:57The Sense of Self: Reflected Self-Appraisal and Social Comparison
56.1K
According to Charles Cooley, we base our image on what we think other people see (Cooley 1902). We imagine how we must appear to others, then react to this speculation. We don certain clothes, prepare our hair in a particular manner, wear makeup, use cologne, and the like—all with the notion that our presentation of ourselves is going to affect how others perceive us. We expect a certain reaction, and, if lucky, we get the one we desire and feel good about it. But more than that, Cooley...
56.1K
01:16Local Anesthetics: Clinical Application as Intravenous Regional Anesthesia
1.3K
Intravenous regional anesthesia or the Bier block technique is used to anesthetize a specific limb or extremity. It uses exsanguinated or blood-drained vessels to transport local anesthetics or LAs to the peripheral nerve trunks. Lidocaine without vasoconstrictors like epinephrine is most commonly used for this technique. Other drugs used are prilocaine, ropivacaine, and chloroprocaine. Bupivacaine is not recommended for this technique due to its high cardiac toxicity.
One of the advantages of...
One of the advantages of...
1.3K
01:13Multiple Comparison Tests
4.5K
Multiple comparison test, abbreviated as MCT, is a post hoc analysis generally performed after comparing multiple samples with one or more tests. An MCT will help identify a significantly different sample among multiple samples or a factor among multiple factors.
It would be easy to compare two samples using a significance alpha level of 0.05. In other words, there is only one sample pair to be compared. However, it would be difficult to identify a significantly different sample if the number...
It would be easy to compare two samples using a significance alpha level of 0.05. In other words, there is only one sample pair to be compared. However, it would be difficult to identify a significantly different sample if the number...
4.5K