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Asthma is associated with increased probability of needing CPAP in children with severe obstructive sleep apnea

Sasikumar Kilaikode1, Miriam Weiss1, Rosemary Megalaa1

  • 1Division of Pulmonary and Sleep Medicine, Children's National Health System, Washington, District of Columbia.

Pediatric Pulmonology
|January 12, 2019
PubMed

Insights

Children with severe obstructive sleep apnea syndrome (OSAS) and asthma are more likely to require continuous positive airway pressure (CPAP) therapy. This finding holds true regardless of other factors, highlighting asthma

Area of Science:

  • Pediatric Pulmonology
  • Sleep Medicine
  • Respiratory Health

Background:

  • Obstructive sleep apnea syndrome (OSAS) in children presents unique challenges for treatment initiation.
  • Asthma frequently co-occurs with OSAS in pediatric populations.
  • Understanding factors influencing CPAP therapy need in severe OSAS is crucial.

Purpose of the Study:

  • To investigate the impact of asthma on the requirement for CPAP therapy in children diagnosed with severe OSAS.
  • To identify distinct features of children with severe OSAS who necessitate CPAP, with a focus on asthma's role.

Main Methods:

  • A cross-sectional study design was employed.
  • Clinical data, risk factors, and polysomnogram (PSG) parameters were analyzed for children with severe OSAS (apnea-hypopnea index ≥10/h).
  • The association between asthma and CPAP initiation was assessed, adjusting for covariates.

Main Results:

  • Out of 400 children with severe OSAS, 133 (33%) had asthma.
  • Children with severe OSAS and asthma showed a significantly higher CPAP need (29%) compared to those without asthma (14%).
  • Multivariate analysis confirmed asthma's independent association with CPAP need, irrespective of demographics, OSAS severity, obesity, or prior adenotonsillectomy.

Conclusions:

  • Asthmatic children with severe OSAS have a greater likelihood of requiring CPAP therapy.
  • This association remains significant even after accounting for other relevant variables.
  • The presence of asthma may be a key indicator influencing CPAP therapy decisions in pediatric severe OSAS.
Abstract

Keywords:
continuous positive airway pressureobstructive sleep apnea syndromepediatric asthma

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