Related Experiment Video
Updated: Jan 30, 2026

Synthesis and Reaction Chemistry of Nanosize Monosodium Titanate
Published on: February 23, 2016
Protective Effect Of Vitamin C On Monosodium Glutamate Induced Changes In The Oviduct Of Rats
Sumaira Abbasi1, Saima Mumtaz Khattak1, Sana Malik1
1Department of Anatomy, Federal Medical and Dental College, Islamabad, Pakistan.
Background:
This study was conducted to evaluate the effect of Vitamin C on Monosodium Glutamate induced histopathological changes in oviduct of adult female Sprague Dawley rats. The duration of study was 6 months. It was an analytical experimental randomized control trial.
Methods:
In this experimental study, 45 female adult Sprague Dawley rats of 10-14 weeks were used and divided into 3 groups. Each group contains 15 rats. Control group (C) received standard laboratory diet. Experimental group A, was given Monosodium Glutamate (0.08 mg/kg body weight/ day) whereas experimental group B, was served on both MSG and Vitamin C (250 mg/kg body weight/day). All groups received diet for a period of 4 weeks. After 4 weeks all rats were sacrificed and oviducts were obtained. For the study of tissue under light microscopy, tissue processing was done by using Haematoxylin and Eosin stain and 5micrometer thick sections were taken from the ampullary part of oviduct.
Results:
After administration of MSG, group A showed vacuolization of epithelial cells, infiltration of RBCs in lumen with substantial decrease in the diameter of oviduct in group A. Protective effects were seen in vitamin C supplemented group B, with decrease in epithelial vacuolization and RBCs infiltrate along with increase in diameter of oviduct.
Conclusions:
Vitamin C has protective effect on Monosodium Glutamate induced histological changes in oviduct of rats.
More Related Videos
12:56Methodology for Biomimetic Chemical Neuromodulation of Rat Retinas with the Neurotransmitter Glutamate In Vitro
Published on: December 19, 2017
07:44Microdissection and Dissociation of the Murine Oviduct: Individual Segment Identification and Single Cell Isolation
Published on: November 4, 2021
Related Concept Videos
Vitamins
Antiepileptic Drugs: Glutamate Antagonists
Protection of Alcohols
Protection
It defines a protecting group as the masking agent to make the more reactive species inert to a given set of conditions. This concept is depicted via the illustration of liquid flow through different outlets in an assembly of pipes. The analogy helps to understand the role...
Zones of Protection
Protective zones are defined by closed dashed lines, containing one or more components. A key characteristic of these zones is the strategic placement of...
Radial System Protection
In a radial system with a fault downstream of the third breaker, ideally, only the third breaker will open, isolating the fault and interrupting the load connected beyond it. The second breaker has a longer delay setting,...
Protecting Self-Esteem