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Updated: Jan 30, 2026

Minimal Invasive Resection of Large Retrosternal Thyroid Goiter
Published on: September 20, 2024
Minimally Invasive Video-Assisted Thyroidectomy: Analysis of Complications From a Systematic Review
Gregorio Scerrino1, Giuseppina Melfa1, Cristina Raspanti1
11 University of Palermo, Palermo, Italy.
Background:
Nowadays, minimally invasive video-assisted thyroidectomy (MIVAT) is considered a safe and effective option. However, its complication rate has not been specifically discussed yet. The aim of this systematic review was enrolling a large number of studies to estimate early and late complications (transient and definitive, uni- and bilateral laryngeal nerve palsy; transient and definitive hypocalcemia; cervical hematoma; hypertrophic or keloid scar) of MIVAT compared with conventional technique.
Methods:
The review was performed according to PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) criteria in PubMed and Embase. Search terms were "minimally invasive," "video-assisted," and "thyroidectomy." We enrolled randomized clinical trials, nonrandomized trials, and noncontrolled trials.
Results:
Thirty-two articles were considered suitable. Complication rate of MIVAT was quite similar to conventional technique: only one randomized trial found a significant difference concerning overall skin complication, and a single trial highlighted hypocalcemia significantly increased in MIVAT, concerning serologic value only. No difference concerning symptomatic nor definitive hypocalcemia was found.
Conclusions:
We can confirm that MIVAT is a safe technique. It should be adopted in mean-high-volume surgery centers for thyroidectomy, if a strict compliance with indication was applied.
Insights
Minimally invasive video-assisted thyroidectomy (MIVAT) shows a complication rate similar to conventional thyroidectomy. This safe surgical technique is recommended for high-volume centers when indications are strictly followed.
Area of Science:
- Surgical Oncology
- Endocrine Surgery
Background:
- Minimally invasive video-assisted thyroidectomy (MIVAT) is a recognized safe and effective thyroid surgery option.
- A comprehensive assessment of MIVAT's complication profile compared to conventional thyroidectomy is needed.
Purpose of the Study:
- To systematically review and estimate the early and late complication rates of MIVAT versus conventional thyroidectomy.
- To analyze complications including laryngeal nerve palsy, hypocalcemia, cervical hematoma, and scarring.
Main Methods:
- Systematic review conducted following PRISMA criteria.
- Searches performed in PubMed and Embase using terms: 'minimally invasive,' 'video-assisted,' and 'thyroidectomy.'
- Included randomized clinical trials, nonrandomized trials, and noncontrolled trials.
Main Results:
- Thirty-two articles were included in the analysis.
- MIVAT demonstrated a complication rate comparable to the conventional technique.
- One study noted increased overall skin complications with MIVAT, and another found a significant increase in serologic hypocalcemia, but no difference in symptomatic or definitive hypocalcemia.
Conclusions:
- MIVAT is confirmed as a safe thyroidectomy procedure.
- The technique is suitable for adoption in high-volume thyroidectomy centers.
- Strict adherence to patient selection criteria is essential for optimal outcomes.
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