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Published on: February 16, 2018
Diastereoselective Synthesis of Polysubstituted Spirocyclopenta[ c]furans by Gold-Catalyzed Cascade Reaction
Jialin Qi1, Qi Teng1, Nuligonda Thirupathi1
1Key Lab for Colloid and Interface Chemistry of Education Ministry , Shandong University , No. 27 Shanda South Road , Jinan 250100 , China.
Abstract:
With the synergistic activation of alkynyl alcohols and alkynyl enones by a single gold catalyst, diverse multisubstituted spirocyclopenta[ c]furans were synthesized in good to excellent yields under mild conditions. Three rings were constructed efficiently in one pot from easily available acyclic starting materials.
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