Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Postviral fatigue syndrome.

P O Behan1, W M Behan

  • 1Department of Neurology, University of Glasgow, Scotland.

Critical Reviews in Neurobiology
|January 1, 1988
PubMed
Summary
This summary is machine-generated.

Myalgic Encephalomyelitis, or post-viral fatigue syndrome, is a complex disorder characterized by profound exhaustion and cognitive difficulties. Current research suggests a metabolic disorder linked to persistent viral infections may be the underlying cause.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Abstracts of the proceedings of the 20th annual meeting of the irish neurological association held on 25th-26th may, 1984.

Irish journal of medical science·2016
Same author

Abnormalities of carnitine metabolism in chronic fatigue syndrome.

European journal of neurology·2013
Same author

Myasthenic crisis.

QJM : monthly journal of the Association of Physicians·2008
Same author

Treatment of multiple sclerosis: beyond the NICE guidelines.

QJM : monthly journal of the Association of Physicians·2005
Same author

In vivo magnetic resonance spectroscopy in chronic fatigue syndrome.

Prostaglandins, leukotrienes, and essential fatty acids·2004
Same author

Molecular mimicry in type 1 diabetes: immune cross-reactivity between islet autoantigen and human cytomegalovirus but not Coxsackie virus.

Annals of the New York Academy of Sciences·2002
Same journal

Dopaminergic modulation of the neuron activity in the cerebral cortex of the wakeful animal.

Critical reviews in neurobiology·2010
Same journal

A new conceptual understanding of brain function: basic mechanisms of brain-initiated normal and pathological behaviors.

Critical reviews in neurobiology·2009
Same journal

Psychiatric implications of hepatitis-C infection.

Critical reviews in neurobiology·2009
Same journal

Methylphenidate treated at the test cage--dose-dependent sensitization or tolerance depend on the behavioral assay used.

Critical reviews in neurobiology·2009
Same journal

Cerebellar-dependent learning as a neurobehavioral index of the cannabinoid system.

Critical reviews in neurobiology·2009
Same journal

The role of intermediate filament proteins in the development of neurological disease.

Critical reviews in neurobiology·2009
See all related articles

Area of Science:

  • Neurology
  • Immunology
  • Infectious Diseases

Background:

  • Myalgic Encephalomyelitis (ME), also known as post-viral fatigue syndrome, is a recognized disorder with varied historical names.
  • This condition can manifest in both epidemic and sporadic forms, affecting patient populations worldwide.
  • Patients commonly report debilitating exhaustion, muscle pain, and significant cognitive impairments, including memory and concentration deficits.

Purpose of the Study:

  • To summarize the current understanding of Myalgic Encephalomyelitis (ME) / post-viral fatigue syndrome.
  • To highlight the diverse symptomatology and potential etiological factors.
  • To present emerging research findings on the disorder's cause.

Main Methods:

  • Review of existing literature on ME and related conditions.

Related Experiment Videos

  • Analysis of patient-reported symptoms and epidemiological data.
  • Synthesis of current research hypotheses regarding the disorder's pathophysiology.

    • Main Results:

    • ME/post-viral fatigue syndrome presents with profound fatigue, myalgia, and psychiatric symptoms like depression and cognitive dysfunction.
    • The exact cause remains unknown, but the disorder is often preceded by viral infections.
    • Emerging research indicates a potential metabolic disorder secondary to persistent viral infection as a leading hypothesis.

    Conclusions:

    • Myalgic Encephalomyelitis/post-viral fatigue syndrome is a significant health concern with complex symptoms.
    • Persistent viral infections and subsequent metabolic disturbances are implicated as potential causes.
    • Further research into the metabolic and infectious links is crucial for understanding and treating ME.