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Published on: September 14, 2021
Synergetic roles of TGF-β signaling in tissue engineering
1Deparment of Pharmacology, College of Medicine, University of Arizona, USA.
Abstract:
Recent advances in tissue engineering highlight biomaterial designs with context-specific growth factors, cytokines and various small molecules to better mimic the natural extracellular matrix (ECM) microenvironments. These efforts have led to direct improvements in cell-cell and cell-ECM interactions while mitigating undesirable cellular and immunogenic responses. In this short review, we focus on the crucial roles and regulation of transforming growth factor β (TGF-β) signaling in biomaterial applications during tissue repair and regeneration.
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