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A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data
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Geographic variations of multiple sclerosis in Iran: A population based study
Ali Hosseinzadeh1, Mohammad Reza Baneshi1, Behnaz Sedighi2
1Modeling in Health Research Center, Institute for Futures Studies in Health, Kerman University of Medical Sciences, Kerman, Iran.
Multiple Sclerosis and Related Disorders
|January 12, 2019
Summary
The incidence of Multiple Sclerosis (MS) in Iran is 6.5 per 100,000, with higher rates in women. Significant geographical variations in MS occurrence were observed across the country.
Area of Science:
- Neurology
- Epidemiology
- Public Health
Background:
- The epidemiology of Multiple Sclerosis (MS) has evolved globally.
- Understanding MS incidence and geographical distribution in Iran is crucial.
- Previous data on MS epidemiology in Iran is limited.
Purpose of the Study:
- To determine the incidence rate of Multiple Sclerosis (MS) in Iran.
- To investigate the geographical variations in MS incidence within Iran.
Main Methods:
- Utilized data from a comprehensive national MS patient registry coordinated by the Ministry of Health.
- Calculated annual incidence rates based on the year of MS diagnosis.
- Ensured data comprehensiveness due to universal patient eligibility for care and treatment services.
Main Results:
- Recorded 32,633 new MS cases between 2011 and 2016.
- The age-standardized mean annual incidence rate was 6.5 per 100,000 population.
- Incidence was higher in women (10.2 per 100,000) than men (2.9 per 100,000), with provincial rates varying from 1.7 to 12.8.
Conclusions:
- The overall incidence and female-to-male ratio of MS in Iran align with patterns observed in developed countries.
- Considerable geographical disparities in MS incidence exist within Iran.
- Further research into the drivers of these geographical variations is warranted.
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