Related Experiment Video

Updated: Jan 30, 2026

Assessing the Coherence of Parents' Short Narratives Regarding their Child Using the Five-Minute Speech Sample Procedure
07:56

Assessing the Coherence of Parents' Short Narratives Regarding their Child Using the Five-Minute Speech Sample Procedure

Published on: September 19, 2019

10.8K

Child-Pugh Classification: Time to Abandon?

Beverley Kok1, Juan G Abraldes1

  • 1Division of Gastroenterology (Liver Unit), University of Alberta, Edmonton, Canada.

Seminars in Liver Disease
|January 12, 2019
PubMed

Insights

The Child-Pugh classification, a common tool for cirrhosis prognosis, requires reassessment. This review examines its limitations and specific applications, including acute variceal bleeding and hepatocellular carcinoma management.

Area of Science:

  • Hepatology
  • Clinical Prognostics
  • Medical Decision-Making

Background:

  • The Child-Pugh classification is a widely used bedside tool for assessing prognosis in cirrhosis patients.
  • Despite its long-standing use, questions exist regarding its accuracy and applicability in modern clinical practice.

Purpose of the Study:

  • To critically evaluate the inherent limitations of the Child-Pugh classification.
  • To reassess its utility in specific clinical scenarios, including acute variceal bleeding, hepatocellular carcinoma, and drug development.

Main Methods:

  • This study is a review of existing literature and clinical applications of the Child-Pugh classification.
  • Analysis focuses on specific contexts where its predictive or decision-making value may be suboptimal.

Main Results:

  • The review identifies several inherent issues within the Child-Pugh classification that may affect its reliability.
  • Its application in acute variceal bleeding, hepatocellular carcinoma management, and drug dosing warrants careful consideration and potential revision.

Conclusions:

  • The current application of the Child-Pugh classification in various clinical contexts, particularly for risk prediction and treatment decisions, needs re-evaluation.
  • Further research and updated guidelines may be necessary to refine its use in managing cirrhosis patients.

More Related Videos

Making MR Imaging Child's Play - Pediatric Neuroimaging Protocol, Guidelines and Procedure15:18

Making MR Imaging Child's Play - Pediatric Neuroimaging Protocol, Guidelines and Procedure

Published on: July 30, 2009

18.7K
Assessment of Child Anthropometry in a Large Epidemiologic Study09:36

Assessment of Child Anthropometry in a Large Epidemiologic Study

Published on: February 2, 2017

27.9K

Related Concept Videos

Force Classification01:22

Force Classification

Forces play a crucial role in the study of physics and engineering. They are essential in describing the motion, behavior, and equilibrium of objects in the physical world. Forces can be classified based on their origin, type, and direction of action.
Contact and non-contact forces are two of the most widely used categories of forces. As the name suggests, contact forces require physical contact between two objects to act upon each other. Examples of contact forces include frictional,...
2.4K
Classification of Neurotransmitters01:30

Classification of Neurotransmitters

Neurotransmitters play a crucial role in the communication between neurons in the autonomic nervous system. Neurons in the autonomic nervous system can be cholinergic or adrenergic depending on the neurotransmitters synthesized. Cholinergic neurons use acetylcholine as their primary neurotransmitter. This includes all the preganglionic fibers of the sympathetic and pre- and postganglionic fibers of the parasympathetic nervous systems. In addition, neurons of the somatic nervous system also use...
5.3K
Classification of Leukocytes01:30

Classification of Leukocytes

Leukocytes are classified into two groups based on the presence or absence of cytoplasmic granules. Granular leukocytes, which contain granules, belong to the myeloid lineage and are divided into three subtypes: neutrophils, eosinophils, and basophils. These cells are roughly spherical and characterized by the granules in their cytoplasm.
Neutrophils are the most abundant type of granular leukocytes, comprising 50-70% of all leukocytes. They feature small, evenly distributed granules and a...
5.8K
Classification of Illness01:17

Classification of Illness

The meaning of illness is individualized to each person who experiences an alteration in health. In contrast, disease is a medical term indicating a pathological change in the structure and function of the body or mind. It is a condition that has specific symptoms and boundaries.
An illness is a response to a disease in which the person's level of functioning is changed compared with a previous level. The general classification of illness includes acute and chronic.
Acute illness is severe...
8.7K
Classification of Bones01:18

Classification of Bones

The bones of the human skeletal system are of varied shapes, sizes, and functions. They can be classified based on their shape and function into four major classes: long bones, short bones, flat bones, and irregular bones. Some classifications include a fifth type, the sesamoid bones, as a separate class, whereas others categorize them under short bones.
Long and Short Bones
The appendicular skeleton, particularly the upper and lower limbs, is primarily made of long and short bones. The...
9.9K
Seizures: Classification01:13

Seizures: Classification

Epilepsy is primarily characterized by unpredictable seizures, either provoked by an identifiable factor, such as injury or illness, or unprovoked, occurring spontaneously without apparent cause.
Seizures are typically classified into two main categories: focal and generalized seizures.
Focal Seizures
Focal seizures originate from specific regions of the brain. These seizures are further sub-classified into two types:
1.6K