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Long-Term Prognosis of Patients with Obscure Gastrointestinal Bleeding: A Retrospective Cohort Study

Makoto Arai1, Tomoaki Matsumura2, Yuki Ohta2

  • 1Department of Clinical Oncology, Graduate School of Medicine, Chiba University, Chiba, Japan, araim-cib@umin.ac.jp.

Digestion
|January 14, 2019
PubMed

Insights

Patients with obscure gastrointestinal bleeding (OGIB) have a poor long-term prognosis, particularly the elderly and those with liver cirrhosis. Capsule endoscopy (CE) is a key diagnostic tool for OGIB.

Area of Science:

  • Gastroenterology
  • Internal Medicine
  • Medical Prognosis

Background:

  • Obscure gastrointestinal bleeding (OGIB) presents diagnostic challenges.
  • Capsule endoscopy (CE) is a valuable tool for investigating OGIB.
  • Long-term outcomes for OGIB patients require further elucidation.

Purpose of the Study:

  • To evaluate the long-term prognosis of patients diagnosed with OGIB via capsule endoscopy (CE).
  • To identify prognostic factors influencing survival in OGIB patients.

Main Methods:

  • A cohort of 259 OGIB patients undergoing CE between 2007-2012 were followed.
  • Clinical characteristics, including age, bleeding type, and comorbidities, were recorded.
  • Survival data was collected from medical institutions for over 5 years post-CE.

Main Results:

  • Of 240 analyzed patients, 57 (23.8%) died within the follow-up period.
  • Five-year survival rate was 74.7%.
  • Advanced age (≥65 years) and liver cirrhosis were significant predictors of poor prognosis.

Conclusions:

  • Obscure gastrointestinal bleeding (OGIB) is associated with a significant mortality risk.
  • Elderly patients and those with liver cirrhosis face a particularly poor prognosis.
  • Capsule endoscopy aids in diagnosing OGIB and assessing patient risk stratification.
Abstract

Keywords:
Capsule endoscopyLong-term prognosisObscure gastrointestinal bleeding

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