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A Curated, Comprehensive Database of Plasmid Sequences.

Lauren Brooks1, Mo Kaze2, Mark Sistrom2

  • 1Utah Valley University, Orem, Utah, USA.

Microbiology Resource Announcements
|January 15, 2019
PubMed
Summary
This summary is machine-generated.

A comprehensive database of 10,892 microbial plasmid sequences was created. This resource compiles data from NCBI and annotated bacterial genomes, offering valuable metadata for researchers studying microbial genetics.

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Area of Science:

  • Microbiology
  • Genomics
  • Bioinformatics

Background:

  • Plasmids are crucial extrachromosomal DNA elements in microorganisms, influencing diverse cellular functions and adaptations.
  • Understanding plasmid diversity and genetic content is essential for fields such as microbial ecology, evolution, and biotechnology.

Purpose of the Study:

  • To create a centralized, curated database of complete plasmid sequences and associated metadata.
  • To facilitate research on microbial plasmids by providing a readily accessible data resource.

Main Methods:

  • Data acquisition from NCBI's updated genome database, including entries where plasmids are listed as organisms.
  • Inclusion of all available annotated bacterial genomes to identify and extract plasmid sequences.
  • Compilation and curation of associated metadata for each plasmid sequence.

Main Results:

  • A database containing 10,892 complete plasmid sequences has been successfully compiled.
  • Associated metadata, including genetic information and source organism details, has been curated for each plasmid.

Conclusions:

  • The established plasmid sequence database serves as a valuable resource for the scientific community.
  • This comprehensive dataset will support future investigations into plasmid biology, function, and evolution across microbial species.