Effect of nicardipine on angiotensin II platelet content

¹Università di Roma La Sapienza, Istituto di l Clinica Medica, Rome, Italy.

Journal of Hypertension. Supplement : Official Journal of the International Society of Hypertension

|November 1, 1988

Abstract:

We evaluated the effect of nicardipine treatment on platelet angiotensin II content in 18 essential hypertensive patients. Nicardipine induced a decrease in platelet angiotensin II content in all patients (-14%), but particularly in 10 (P less than 0.05; -20.5%). No other differences were found between these patients and the others. Further investigations are required to determine whether platelet angiotensin II content reduction contributes to the prophylactic and therapeutic effects of calcium antagonists on atherosclerosis.

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Effect of nicardipine on angiotensin II platelet content

Abstract:

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