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Updated: Jan 30, 2026

Isolation and Analysis of Hematopoietic Stem Cells from the Placenta
Published on: June 24, 2008
First-trimester abortion complicated with placenta accreta: A systematic review
Yeou-Lih Wang1, Shih-Shien Weng1, Wen-Chu Huang1
1Department of Obstetrics and Gynecology, Mackay Memorial Hospital, Taipei, Taiwan; Mackay Medicine, Nursing and Management College, Taipei, Taiwan; Mackay Medical College, Taipei, Taiwan.
Placenta accreta after a first-trimester abortion is rare but serious. Key risk factors include prior uterine surgeries and advanced maternal age, necessitating high clinical suspicion for prompt diagnosis and management.
Area of Science:
- Reproductive Medicine
- Gynecology
- Obstetrics
Background:
- Placenta accreta is a rare but severe complication of first-trimester abortion.
- Early recognition and management are crucial due to potential life-threatening outcomes.
Purpose of the Study:
- To review the literature on first-trimester postabortal placenta accreta.
- To identify risk factors, clinical presentations, and management strategies.
Main Methods:
- Systematic literature review of PubMed-indexed English journals up to August 2018.
- Inclusion of 19 articles and 23 case reports on first-trimester postabortal placenta accreta.
Main Results:
- Significant risk factors include previous cesarean section (87%), uterine curettage (43.5%), and advanced maternal age (≥35 years, 43.5%).
- Clinical presentation commonly involves vaginal bleeding with variable onset (immediate to delayed).
- Conservative management (e.g., UAE, TACE) may be attempted, but hysterectomy is often the definitive treatment.
Conclusions:
- A high index of clinical suspicion is essential for early diagnosis of postabortal placenta accreta.
- Prompt management improves outcomes for this emergent obstetric condition.
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