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Updated: Jan 30, 2026

Rat Burn Model to Study Full-Thickness Cutaneous Thermal Burn and Infection
Published on: August 23, 2022
Infant burns: A single institution retrospective review
C Brink1, Q Isaacs1, M F Scriba1
1Department of Paediatric Surgery, Red Cross War Memorial Children's Hospital and Faculty of Health Sciences, University of Cape Town, South Africa.
Insights
Infant thermal injuries in South Africa are common, often occurring in homes due to scalds. This study highlights the need for specialized care for infants, as surgical treatment led to more complications than conservative management.
Area of Science:
- Pediatric Burn Research
- Infant Injury Prevention
- Public Health in South Africa
Background:
- Infant thermal injuries are a significant cause of mortality and morbidity in South Africa.
- Poverty and immature infant development contribute to unsafe living conditions and increased burn risks.
- Infants rely heavily on their environment and caregivers for safety.
Purpose of the Study:
- To analyze the characteristics, causes, and outcomes of thermal injuries in infants admitted to a hospital.
- To identify risk factors and trends in infant burn admissions.
- To inform specialized treatment strategies for this vulnerable pediatric subgroup.
Main Methods:
- Retrospective observational study of 548 infant admissions (under 13 months) over 48 months.
- Data collected on demographics, injury type, Total Body Surface Area (TBSA), environment, and treatment.
- Analysis of complications, infections, Intensive Care Unit (ICU) admissions, and mortality rates.
Main Results:
- Infants constituted 23% of pediatric burn admissions (0-12 years).
- Scalds were the predominant injury (86%), primarily occurring in the home environment (76%).
- Surgically treated infants experienced more complications than those managed conservatively; mortality rate was 0.36%.
Conclusions:
- Thermal injuries in infants, particularly scalds, are a major concern in South Africa, often linked to home environments.
- Ambulatory infants (7-12 months) were more common than pre-ambulatory infants (0-6 months).
- Specialized treatment considerations are crucial for infants, as surgical interventions may lead to increased complications compared to conservative approaches.
Abstract:
Thermal injuries amongst infants are common and a cause of significant mortality and morbidity in South Africa. This has been attributed to the lack of an enabling environment (poverty-related lack of safe living conditions) and the cognitive and physical developmental immaturity of infants, who depend on their surroundings and adults to keep them safe. This is a retrospective observational study of 548 infant admissions over 48 months. Infant was defined as children below 13 months of age. The 548 infants constituted 23% of all paediatric burn admissions of ages 0-12 years. Three hundred and fourteen were males (57%) and 234 (42.7%) females. The infants were divided in a pre-ambulatory group of 143 (26%) infants of 0-6 months and an ambulatory group of 7 months to 12 months consisting of 457 (83.3%). The total body surface area (TBSA) ranged from 2-65%. Seventy-six percent (417 infants) occurred in the home environment. Scalds accounted for 86% (471 infants) and 6% (33 infants) were as a result of flame burns. Non-accidental injuries accounted for 1.2%. The anatomical distributions varied between the pre-ambulatory and ambulatory groups. Conservative management was done in 397 (72.4%) and 101(18.4%) infants underwent surgery. Infection was suspected in 76 (13.5%) infants with positive blood cultures in 15(20%) of the 76. ICU care was received in 46 (8.3%) infants and 15 (32.6%) of these had inhalation injuries. Of the inhalation injuries 11(23.9%) infants underwent mechanical ventilation of an average of 4.4 days. Ventilator associated pneumonia was diagnosed in 8(17%) of the ventilated children. The mortality rate was 0.36%. The surgically treated patients acquired more complications than the conservatively treated group. Special treatment considerations should be considered in this paediatric sub-group.
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