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Updated: Jan 30, 2026

Oral Combinational Antiretroviral Treatment in HIV-1 Infected Humanized Mice
Published on: October 6, 2022
[HIV, antiretroviral therapy and suicidal behaviour: a multidisciplinary case report and underlying
Abstract:
The relationship between hiv, major depressive disorder and suicidal ideation is well established. For example, hiv-positive patients are seven times more likely to develop depression, and suicidal behaviour is also more prevalent. Antiretroviral therapy is known to further enhance these risks. We saw a 53-year-old patient with a depressive episode and suicidal ideation, possibly related to the use of dolutegravir/abacavir/lamivudine. We provide an overview of the literature and we present a neuro-immunological hypothesis for this psychiatric adverse event, which may occur even after months of treatment.
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