First international consensus on the diagnosis and management of fibromuscular dysplasia
Heather L Gornik1, Alexandre Persu2, David Adlam3,4
1Division of Cardiovascular Medicine, Department of Cardiovascular Medicine, University Hospitals Cleveland Medical Center and UH Harrington Heart and Vascular Institute, Cleveland, Ohio, USA.
Insights
This updated guideline offers comprehensive diagnosis and management strategies for fibromuscular dysplasia (FMD). It harmonizes European and US expert recommendations, incorporating registry data and future research directions for this arterial disease.
Area of Science:
- Cardiology
- Vascular Medicine
- Nephrology
Background:
- Fibromuscular dysplasia (FMD) is a complex arterial disease requiring updated consensus.
- Previous guidelines from 2014 necessitate revision based on new data and expert consensus.
Framework:
- Harmonized recommendations from European Society of Hypertension (ESH) and Society for Vascular Medicine (SVM) experts.
- Integration of data from the European/International FMD Registry and the US FMD Registry.
Implementation:
- Provides practical, consensus-based clinical recommendations for FMD diagnosis and management.
- Includes a consensus protocol for catheter-based angiography and percutaneous angioplasty for renal FMD.
Implications:
- Offers a unified approach for European and US clinicians managing FMD.
- Highlights ongoing research and proposes future directions for understanding FMD.
- Aims to improve patient outcomes through standardized, evidence-based care.
Abstract:
This article is a comprehensive document on the diagnosis and management of fibromuscular dysplasia (FMD) which was commissioned by the Working Group 'Hypertension and the Kidney' of the European Society of Hypertension (ESH) and the Society for Vascular Medicine (SVM). This document updates previous consensus documents/scientific statements on FMD published in 2014 with full harmonization of the position of European and US experts. In addition to practical consensus-based clinical recommendations, including a consensus protocol for catheter-based angiography and percutaneous angioplasty for renal FMD, the document also includes the first analysis of the European/International FMD Registry and provides updated data from the US Registry for FMD. Finally, it provides insights on ongoing research programs and proposes future research directions for understanding this multifaceted arterial disease.
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