Related Experiment Video
Updated: Jan 30, 2026

05:48
Lung Fixation under Constant Pressure for Evaluation of Emphysema in Mice
Published on: September 26, 2019
9.9K
Bronchoscopic Lung Volume Reduction in Patients with Severe Emphysema
Sebastian Fernandez-Bussy1, Gonzalo Labarca2,3, Felix J F Herth4
1Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Jacksonville, Florida.
Seminars in Respiratory and Critical Care Medicine
|January 15, 2019
Summary
Bronchoscopic lung volume reduction (BLVR) offers a minimally invasive option for severe emphysema, improving patient outcomes. This review details current BLVR techniques, their effectiveness, and safety profiles.
Area of Science:
- Pulmonary Medicine
- Interventional Pulmonology
- Respiratory Disease Management
Background:
- Severe emphysema significantly impacts patient quality of life and lung function.
- Surgical lung volume reduction is not suitable for all patients.
- Bronchoscopic lung volume reduction (BLVR) presents a less invasive alternative.
Purpose of the Study:
- To review current bronchoscopic lung volume reduction (BLVR) techniques.
- To evaluate the efficacy and safety of various BLVR methods.
- To provide data on patient selection for BLVR.
Main Methods:
- Review of published data on different BLVR strategies.
- Analysis of blocking (valves) and non-blocking (coils, ablation) techniques.
- Assessment of radiographic and pulmonary function testing in candidate selection.
Main Results:
- BLVR improves functional and clinical outcomes in selected emphysema patients.
- The risk of severe complications with BLVR is relatively low.
- Different BLVR techniques demonstrate varying benefits and risks.
Conclusions:
- Bronchoscopic lung volume reduction (BLVR) is a viable option for symptomatic severe emphysema.
- Optimal patient selection and treatment are crucial for successful BLVR.
- Further data supports the efficacy and safety of current BLVR approaches.
Related Concept Videos
Lung Capacity
56.3K
The air in the lungs is measured in volumes and capacities. Lung volume measures reflect the amount of air taken in, released, or left over after a lung function, like a single inhalation. Lung capacity measures are sums of two or more lung volume measures.
56.3K
Oxidation-Reduction Reactions
75.6K
Oxidation–Reduction Reactions
75.6K
Constant Volume Calorimetry
30.7K
Calorimeters are useful to determine the heat released or absorbed by a chemical reaction. Coffee cup calorimeters are designed to operate at constant (atmospheric) pressure and are convenient to measure heat flow (or enthalpy change) accompanying processes that occur in solution at constant pressure. A different type of calorimeter that operates at constant volume, colloquially known as a bomb calorimeter, is used to measure the energy produced by reactions that yield large amounts of heat and...
30.7K
Volume of Distribution
1.3K
The apparent volume of distribution (Vd) is a crucial pharmacokinetic parameter representing the hypothetical body fluid volume into which a drug disperses. It is calculated based on the total amount of drug in the body (estimated from the administered dose and bioavailability) divided by the plasma drug concentration. The total amount of drug in the body does not directly refer to the dose given but is derived by accounting for absorption, distribution, metabolism, and excretion processes.
1.3K
Problem Solving: Volume
69
The volume of a fuel tank mounted on the wing of a jet aircraft can be modeled using the concept of solids of revolution. In this case, the tank is formed by rotating a two-dimensional region, defined by a mathematical function, about the x-axis. The region extends along the axis from zero to two meters, and the resulting three-dimensional shape is symmetric about the axis of rotation. Because the boundary curve lies directly against the axis, the disk method is an appropriate technique for...
69
Respiratory Volumes
3.0K
Respiratory volumes are crucial metrics, meticulously measured to quantify the air exchanged in and out of the lungs during various phases of the breathing cycle. These precise measurements are vital for assessing lung function, diagnosing respiratory conditions, and monitoring overall respiratory health. Each parameter provides specific insights into the mechanics of breathing and the functional capacity of the lungs.
Tidal Volume (TV) Tidal volume (TV) is the air inhaled or exhaled in a...
Tidal Volume (TV) Tidal volume (TV) is the air inhaled or exhaled in a...
3.0K

