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Updated: Jan 30, 2026

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
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Adherence to Treatment in Stroke Patients.

Emmanouela Cheiloudaki1, Evangelos C Alexopoulos2,3

  • 1School of Social Sciences, Hellenic Open University, 26335 Patra, Greece. litsachi@hotmail.com.

International Journal of Environmental Research and Public Health
|January 16, 2019
PubMed
Summary

Medication adherence in stroke survivors is often suboptimal. High compliance is linked to better mental state, perceived medication necessity, and doctor-patient communication, while men and lower quality of life showed reduced adherence.

Keywords:
Greecebeliefscompliancerecoveryrehabilitationreturn to workstroke

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Area of Science:

  • Neurology
  • Public Health
  • Pharmacology

Background:

  • Medication compliance among stroke patients is frequently suboptimal.
  • Long-term adherence is crucial for managing post-stroke recovery and preventing recurrence.
  • Identifying influencing factors is key to improving patient outcomes.

Purpose of the Study:

  • To assess medication compliance levels in long-term stroke survivors.
  • To identify socio-demographic, clinical, and subjective factors associated with treatment adherence.
  • To inform interventions aimed at enhancing medication compliance in this population.

Main Methods:

  • A survey of 140 ischemic stroke patients (at least six months post-stroke).
  • Utilized validated scales for medication adherence, quality of life, beliefs about medicines, illness perception, doctor-patient relationship, and family support.
  • Employed univariate and multivariate analyses to determine significant predictors of compliance.

Main Results:

  • Optimal compliance was observed in 68.6% of patients.
  • High adherence correlated with positive mental state, perceived medication necessity, and effective doctor-patient communication.
  • Lower compliance was associated with male gender, greater concerns about medication, and inverse relationship with work/productivity quality of life.

Conclusions:

  • Perceived medication necessity and doctor-patient communication are modifiable factors influencing stroke patient compliance.
  • Rehabilitation and return-to-work programs should integrate these factors to support stroke survivors.
  • Targeted interventions addressing patient perceptions and communication can improve long-term medication adherence.