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IgG4-related dacryocystitis and aortitis: A new association
Enrique España-Gregori1, Miriam Rahhal-Ortuño1, Véronique Benavent-Corai2
1Department of Ophthalmology, Hospital Universitari i Politecnic La Fe, Valencia, Spain.
This case study highlights IgG4-related dacryocystitis, a rare condition involving IgG4 plasma cell infiltration, which was successfully diagnosed and treated in a 73-year-old woman. The diagnosis led to the identification of associated aortitis.
Area of Science:
- Ophthalmology
- Rheumatology
- Immunology
Background:
- A 73-year-old woman presented with a history of unexplained muscular weakness and dyspnoea.
- She was referred to the Ophthalmology Department for evaluation of dacryocystitis.
Observation:
- Lacrimal sac biopsy was performed to investigate the dacryocystitis.
- Biopsy results revealed significant IgG4 plasma cell infiltration.
Findings:
- The presence of IgG4 plasma cells confirmed IgG4-related dacryocystitis.
- This finding facilitated a systemic diagnosis, revealing an association with aortitis.
Implications:
- This case represents the first reported instance of IgG4-related dacryocystitis linked to aortitis.
- Establishing this connection allows for appropriate treatment strategies for this rare condition.
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