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Author Spotlight: Advancing Research on Candida albicans Biofilm-Associated Prosthetic Joint Infections
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Mortality During Total Hip Periprosthetic Joint Infection
Kyle M Natsuhara1, Trevor J Shelton1, John P Meehan1
1Department of Orthopaedic Surgery, University of California Davis Medical Center, Sacramento, CA.
The Journal of Arthroplasty
|January 16, 2019
Summary
The mortality rate after hip periprosthetic joint infection (PJI) revision surgery is high, with a 1-year mortality of 4.22% and a 5-year mortality of 21.12%. This significantly increases the risk of death compared to the general population.
Area of Science:
- Orthopedic surgery
- Infectious disease
- Public health
Background:
- Periprosthetic joint infection (PJI) is a serious complication following hip replacement surgery.
- Understanding the mortality associated with PJI is crucial for patient management and outcomes.
Purpose of the Study:
- To determine the mortality rate of patients undergoing 2-stage revision surgery for hip periprosthetic joint infection (PJI).
Main Methods:
- A systematic review and meta-analysis of 23 studies.
- Inclusion of 19,169 patients who underwent revision for total hip PJI.
Main Results:
- The weighted 1-year mortality rate following total hip PJI revision was 4.22%.
- The 5-year mortality rate reached 21.12%.
- Patients with total hip PJI faced a 3.58 times higher risk of death compared to age-adjusted national risks (P < .001).
Conclusions:
- Mortality rates associated with total hip revision for infection are substantial.
- Death is a significant complication that must be discussed during patient counseling for hip PJI.
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