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Updated: Jan 30, 2026

An Orthotopic Resectional Mouse Model of Pancreatic Cancer
Published on: September 24, 2020
Aspirin Does Not Prevent Pancreatic Cancer in a Large Asian Cohort
Min-Hyung Kim1,2, Sang Min Park1,2, Young Ho Yun1,2
1Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, South Korea.
Background:
Evidence has suggested that aspirin reduces the incidence of several cancers, but these benefits may not occur with pancreatic cancer.
Methods:
A 12-year nationwide longitudinal cohort merged with the health checkup data was divided into "exposure ascertainment period" and "outcome ascertainment period" to avoid immortal time bias. The daily defined dose system was used to indicate the drug exposure.
Results:
We found no significant association between aspirin use and incident pancreatic cancer based on HR.
Conclusions:
Aspirin does not prevent pancreatic cancer.
Impact:
A large Asian cohort study with reliable medication information affirms no impact of aspirin on pancreatic cancer development.
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