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Engineering Precision Medicine.

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Engineering advancements are paving the way for precision medicine, tailoring treatments based on individual genetic profiles. This personalized healthcare approach promises more effective therapies by leveraging genomic insights and innovative engineering solutions.

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biomaterialscell engineeringorgans‐on‐chipspersonalized devicespersonalized implants

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Area of Science:

  • Biomedical Engineering
  • Genomics
  • Personalized Medicine

Background:

  • Genomic sequencing and bioinformatics enable precision medicine by linking individual genetic makeup to therapeutic outcomes.
  • Cancer genomics research has identified specific genes influencing drug efficacy.

Purpose of the Study:

  • To highlight the crucial role of engineers in advancing precision medicine.
  • To outline various engineering contributions to personalized healthcare.

Main Methods:

  • Engineering biosensors for diagnostics and monitoring.
  • Developing smart drug delivery systems for controlled release.
  • Programming immune cells for targeted cancer therapies.
  • Differentiating stem cells and fabricating tissue scaffolds.
  • Constructing organs-on-chips for drug screening.

Main Results:

  • Engineering offers diverse tools to enhance precision medicine.
  • Materials and cell engineering are key to developing personalized diagnostics and therapeutics.
  • Advanced engineering techniques are critical for realizing the full potential of precision medicine.

Conclusions:

  • Collective engineering efforts are transforming healthcare into a more personalized and effective approach.
  • Continued progress in engineering will provide more tools to fully implement precision medicine.