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Updated: Jan 30, 2026

Trabecular Meshwork Response to Pressure Elevation in the Living Human Eye
Published on: June 20, 2015
[Kahook Dual Blade : An instrument for microincisional trabecular meshwork surgery]
C van Oterendorp1, D Bahlmann2
1Klinik für Augenheilkunde, Universitätsmedizin Göttingen, Robert-Koch-Str. 40, 37075, Göttingen, Deutschland. christian.oterendorp@med.uni-goettingen.de.
The novel Kahook Dual Blade offers an alternative to the Trabectome for opening Schlemm's canal. Clinical data suggest comparable effectiveness and complication rates, including intraocular pressure elevation and hyphema.
Area of Science:
- Ophthalmology
- Glaucoma Surgery
- Surgical Innovation
Background:
- Schlemm's canal is a key target for glaucoma surgery.
- Traditional methods like Trabectome use electroablation.
- A novel dual blade instrument, the Kahook Dual Blade, has been developed.
Purpose of the Study:
- To compare the Kahook Dual Blade with the Trabectome for opening Schlemm's canal.
- To evaluate the effectiveness and safety of the Kahook Dual Blade.
- To assess intraoperative and postoperative complications.
Main Methods:
- Review of limited retrospective studies with follow-up up to 1 year.
- Comparison of procedures performed under gonioscopic control.
- Analysis of effectiveness, intraocular pressure (IOP) elevation, and hyphema.
Main Results:
- The Kahook Dual Blade procedure is comparable to the Trabectome.
- Effectiveness appears similar between the two instruments.
- Intraoperative and postoperative complications, including IOP elevation and hyphema, are comparable.
Conclusions:
- The Kahook Dual Blade is a viable alternative to the Trabectome for opening Schlemm's canal.
- Current data suggest similar efficacy and safety profiles.
- Further research with longer follow-up is warranted.
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