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Updated: Jan 30, 2026

Reverse Microemulsion-mediated Synthesis of Monometallic and Bimetallic Early Transition Metal Carbide and Nitride Nanoparticles
Published on: November 27, 2015
Recent advances in transition metal-catalyzed C(sp2)-H nitration
Li-Rui Song1, Zhoulong Fan, Ao Zhang
1CAS Key Laboratory of Receptor Research and the State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica (SIMM), Chinese Academy of Sciences, Shanghai 201203, China. aozhang@simm.ac.cn.
Abstract:
Nitroaromatic compounds play an important role in organic synthesis, medicinal chemistry and chemical industry. Among the recently reported synthetic methods to access nitroarenes, transition metal-catalyzed C(sp2)-H activation/nitration has become one of the most attractive protocols, showing high regioselectivity, excellent functional group tolerance and step-economy. In this review, we discuss advances in direct C(sp2)-H nitration for the synthesis of nitroaromatic compounds and mechanistic insights over the past decade. We hope this will provide valuable information for researchers interested in the rapidly developing field of metal-catalyzed C(sp2)-H nitration.
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