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Updated: Jan 30, 2026

Rapid Assembly of Multi-Gene Constructs using Modular Golden Gate Cloning
Published on: February 5, 2021
Channel cloning by multi-mode phase-sensitive parametric mixer
Abstract:
We investigate high fidelity channel replication approaching the idealized notion of channel cloning with negligible excess noise and distortion. Previously proposed cloning architectures require that the channel carriers to be externally seeded, limiting their ultimate usefulness, whereas the self-seeded approach limits the channel number and signal-to-noise ratio. Specifically, when a single channel is replicated, the noise figure (NF) remains above the well-known 3-dB limit, and multi-channel replication by a dual-pump driven parametric mixer faces a theoretical NF limit of 6-dB. On the other hand, large-channel-count cloning is of particular importance as it allows for rate scaling in generalized signal processing. Recognizing the limits of conventional architectures that rest on homogeneous parametric mixers, we here propose multi-stage, dispersion-managed parametric mixers in multi-mode phase-sensitive architecture to clone the input signal to a substantial number of channels. In particular, when the new mixer is operated in four-mode phase-sensitive architecture, a 17-copy-count channel cloning with maximum NF less than 6-dB and a record-low NF of 2-dB was experimentally implemented and demonstrated in this paper.
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