Related Experiment Video
Updated: Jan 30, 2026

07:58
Bio-inspired Polydopamine Surface Modification of Nanodiamonds and Its Reduction of Silver Nanoparticles
Published on: November 14, 2018
8.8K
UCSF Protocol for Caries Arrest Using Silver Diamine Fluoride: Rationale, Indications and Consent.
Summary
Silver diamine fluoride is now FDA-cleared for tooth sensitivity and proven in trials to prevent and arrest dental caries. This systematic review guides its application for caries arrest treatment.
Area of Science:
- Dentistry
- Cariology
- Dental Materials
Background:
- The U.S. Food and Drug Administration (FDA) has cleared silver diamine fluoride (SDF) for treating tooth sensitivity.
- Clinical evidence supports the use of SDF for arresting and preventing dental caries.
- The off-label application of SDF for caries arrest is now legally permissible and appropriate.
Purpose of the Study:
- To present a systematic review on the efficacy of silver diamine fluoride for caries arrest.
- To outline clinical indications for SDF application in caries management.
- To provide a clinical protocol and consent procedure for SDF caries arrest treatment.
Main Methods:
- Systematic literature review of clinical trials on silver diamine fluoride for caries arrest.
- Analysis of clinical indications and evidence for SDF efficacy.
- Development of a standardized clinical protocol and patient consent process.
Main Results:
- Silver diamine fluoride is effective in arresting and preventing the progression of dental caries.
- Clinical trials demonstrate significant success rates for SDF in caries arrest.
- A new CDT code facilitates documentation and billing for caries arresting medicaments.
Conclusions:
- Silver diamine fluoride is a viable and effective treatment option for dental caries arrest.
- The systematic review provides evidence-based guidance for the clinical application of SDF.
- Standardized protocols and consent procedures ensure safe and appropriate use of SDF for caries arrest.
Related Concept Videos
Indicators
60.6K
Certain organic substances change color in dilute solution when the hydronium ion concentration reaches a particular value. For example, phenolphthalein is a colorless substance in any aqueous solution with a hydronium ion concentration greater than 5.0 × 10−9 M (pH < 8.3). In more basic solutions where the hydronium ion concentration is less than 5.0 × 10−9 M (pH > 8.3), it is red or pink. Substances such as phenolphthalein, which can be used to determine the pH of a solution, are...
60.6K
Mechanical Ventilation I: Indication and Settings
2.8K
Mechanical ventilation is a life-saving technique for managing acute respiratory failure and other respiratory complications. The process involves using a machine known as a ventilator to supply oxygen to the lungs and assist in removing carbon dioxide. It serves as a bridge to long-term mechanical ventilation or a temporary measure until ventilatory support is discontinued. The ventilator can maintain this function for a prolonged period, providing critical support for patients until they can...
2.8K
Respiratory Assessment: Purpose and Indications
1.8K
Respiratory assessment is a cornerstone of nursing assessments, crucial for the early detection of patient deterioration. This evaluation transcends routine procedures, representing a critical skill nurses must master to ensure optimal patient care.
Objectives and Importance:
The primary goal of respiratory assessment is to evaluate patients at early risk of clinical deterioration. Since respiratory distress often precedes other signs of declining health, breathing patterns and sounds become a...
Objectives and Importance:
The primary goal of respiratory assessment is to evaluate patients at early risk of clinical deterioration. Since respiratory distress often precedes other signs of declining health, breathing patterns and sounds become a...
1.8K
Bioequivalence of Drugs: Drugs with Multiple Indications
158
The concept of therapeutic equivalence (TE) in drugs with multiple indications is complex. A generic drug may be therapeutically equivalent to a brand-name product for one specific indication, but this doesn't necessarily mean it's equivalent for all other indications. Evidence of TE in one patient group and bioequivalence shown in healthy volunteers can support—but not confirm—TE for other indications. However, definitive proof requires individual clinical studies for each...
158
Cardiovascular Drugs: Classification based on Therapeutic Indications
4.2K
Cardiovascular diseases, encompassing a range of conditions, can significantly affect the heart's operations and the overall circulatory system. These conditions impair the heart's ability to pump blood, leading to a deficit in oxygen supply to crucial organs. Anomalies in the heart's electrical system, known as arrhythmias, can cause heartbeats to accelerate or slow down. Usually, heart rates increase during physical activity and decrease while resting or sleeping. However,...
4.2K
Trends in Lattice Energy: Ion Size and Charge
26.7K
An ionic compound is stable because of the electrostatic attraction between its positive and negative ions. The lattice energy of a compound is a measure of the strength of this attraction. The lattice energy (ΔHlattice) of an ionic compound is defined as the energy required to separate one mole of the solid into its component gaseous ions. For the ionic solid sodium chloride, the lattice energy is the enthalpy change of the process:
26.7K

