Related Experiment Video
Updated: Jan 30, 2026

07:06
Fecal Microbiota Transplantation via Colonoscopy for Recurrent C. difficile Infection
Published on: December 8, 2014
27.7K
Success and Complication Rates After Sacral Neuromodulation for Fecal Incontinence and Constipation: A Single-center
Bernhard Widmann1, Christian Galata2, Rene Warschkow1,3
1Department of General, Visceral, Endocrine and Transplantation Surgery, Kantonsspital St. Gallen, Switzerland.
Journal of Neurogastroenterology and Motility
|January 16, 2019
Summary
Sacral neuromodulation (SNM) provides sustainable fecal incontinence treatment. However, its effectiveness for constipation is limited, and reinterventions do not hinder long-term success.
Area of Science:
- Medical Science
- Neurosurgery
- Gastroenterology
Background:
- Sacral neuromodulation (SNM) is a therapeutic option for patients with fecal incontinence (FI) and/or constipation.
- Evaluating the long-term efficacy and sustainability of SNM is crucial for clinical decision-making.
Purpose of the Study:
- To assess the long-term sustainability of sacral neuromodulation (SNM) outcomes in patients treated for fecal incontinence (FI) and/or constipation.
- To determine success rates, complication rates, and reintervention rates associated with SNM therapy.
Main Methods:
- Retrospective analysis of a prospective database of patients who underwent SNM between 2006 and 2015.
- Assessment of success rates, complications, and reinterventions up to 10 years post-implantation.
- Evaluation of patient outcomes including changes in incontinence episodes and need for battery replacement or reintervention.
Main Results:
- Of 101 patients implanted, 79 (78.2%) received permanent SNM, with 72.2% still benefiting at a mean follow-up of 4.4 years.
- The 5-year success rate for FI was 88.2%, significantly higher than for isolated constipation (31.2%).
- Reinterventions were required in 30.4% of patients, but did not negatively impact long-term success rates; median battery life was 6.2 years.
Conclusions:
- Sacral neuromodulation (SNM) demonstrates sustained effectiveness as a treatment for fecal incontinence (FI).
- The long-term efficacy of SNM for constipation is limited, and it is not recommended as a primary therapy.
- While reinterventions are sometimes necessary, they do not compromise the overall success of SNM therapy.
Related Concept Videos
Ecological Succession
21.5K
Ecological succession is influenced by the processes of facilitation, inhibition, and toleration. Facilitation occurs when early successional species create more favorable ecological conditions for subsequent species, such as enhanced nutrient, water, or light availability. In contrast, inhibition happens when early successional species create unfavorable ecological conditions for potential successive species, such as limiting resource availability. In some cases, later successional species...
21.5K
Lattice Centering and Coordination Number
11.5K
The structure of a crystalline solid, whether a metal or not, is best described by considering its simplest repeating unit, which is referred to as its unit cell. The unit cell consists of lattice points that represent the locations of atoms or ions. The entire structure then consists of this unit cell repeating in three dimensions. The three different types of unit cells present in the cubic lattice are illustrated in Figure 1.
Types of Unit Cells
Imagine taking a large number of identical...
Types of Unit Cells
Imagine taking a large number of identical...
11.5K
Hemodialysis II: Procedure and Complications
808
DialyzersA hemodialysis (HD) dialyzer is a plastic cartridge containing thousands of parallel hollow fibers, which serve as semipermeable membranes. These fibers are typically made from cellulose-based or other synthetic materials. During HD, blood is pumped into the top of the cartridge and distributed among these fibers. Simultaneously, dialysis fluid, known as dialysate, is introduced into the bottom of the cartridge, bathing the outside of the fibers. Across the semipermeable membrane,...
808
Center of Gravity
6.7K
The center of gravity (COG) of an object is the point where the object's total weight is considered to be concentrated. Knowing the location of the center of gravity is useful when predicting the behavior of a moving object or designing static structures. In a uniform gravitational field, the center of gravity is similar to the center of mass (COM); yet, these two points can be positioned differently. For example, the Moon's center of mass lies very close to its geometric center, but...
6.7K
Center of Gravity
2.2K
The center of gravity is the point at which an object's weight appears to be concentrated and can be used to balance the object perfectly. This point is essential in mechanics as it provides information regarding a body's stability and moments of inertia. The center of gravity does not always have to fall within the shape or boundaries of the body; it may also lie outside the body in certain cases.
To determine its location, the principle of moments can be utilized by dividing the object into...
To determine its location, the principle of moments can be utilized by dividing the object into...
2.2K
Reaction Rate
63.0K
The rate of reaction is the change in the amount of a reactant or product per unit time. Reaction rates are therefore determined by measuring the time dependence of some property that can be related to reactant or product amounts. Rates of reactions that consume or produce gaseous substances, for example, are conveniently determined by measuring changes in volume or pressure.
The mathematical representation of the change in the concentration of reactants and products, over time, is the rate...
The mathematical representation of the change in the concentration of reactants and products, over time, is the rate...
63.0K

