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Managing vesicoureteral reflux in children: making sense of all the data

Angelena Edwards1, Craig A Peters1

  • 1Children's Health System Texas, University of Texas Southwestern, Dallas, TX, USA.

F1000Research
|January 17, 2019
PubMed

Insights

Current pediatric vesicoureteral reflux (VUR) management evolves with ongoing research. Not all children with VUR need treatment, and risk stratification is key for personalized care.

Area of Science:

  • Pediatric Urology
  • Nephrology
  • Infectious Diseases

Background:

  • Vesicoureteral reflux (VUR) and urinary tract infections (UTIs) in children present complex management challenges.
  • Evolving data and clinical thinking shape current approaches to VUR and UTI in pediatric populations.
  • Controversies persist regarding VUR screening, testing, and intervention effectiveness.

Purpose of the Study:

  • To review the current understanding and management of VUR in children.
  • To highlight areas of consensus and ongoing debate in pediatric VUR management.
  • To emphasize the role of bladder dysfunction and risk stratification in VUR treatment.

Main Methods:

  • Review of current literature and clinical guidelines on pediatric VUR.
  • Analysis of the impact of VUR and UTI on pediatric outcomes.
  • Evaluation of diagnostic and therapeutic strategies for VUR.

Main Results:

  • Consensus exists on the significance of bladder dysfunction in VUR outcomes and resolution.
  • Not all children diagnosed with VUR necessitate active medical or surgical intervention.
  • Risk stratification strategies are emerging as crucial for tailored VUR and UTI management.

Conclusions:

  • Pediatric VUR management is dynamic, influenced by ongoing research and clinical debate.
  • Identifying children who do not require active treatment is essential for optimizing care.
  • Developing robust risk stratification models promises more individualized treatment plans for pediatric VUR and UTI.

Keywords:
Pediatric Vesicoureteral RefluxUrinary tract infectionantibiotic prophylaxisrenal scarring

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