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The MODS method for diagnosis of tuberculosis and multidrug resistant tuberculosis
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The MODS method for diagnosis of tuberculosis and multidrug resistant tuberculosis

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Advances in the diagnosis, treatment, and prevention of tuberculosis in children

Jennifer Furin1

  • 1a Harvard Medical School , Department of Global Health and Social Medicine , Boston , MA , USA.

Expert Review of Respiratory Medicine
|January 17, 2019
PubMed

Insights

Pediatric tuberculosis (TB) remains a major global health issue for children. Innovations in TB diagnosis, treatment, and prevention offer hope for elimination within a decade with adequate support.

Area of Science:

  • Pediatric infectious diseases
  • Public health
  • Global health

Background:

  • Pediatric tuberculosis (TB) is a leading cause of childhood mortality worldwide.
  • Despite recent innovations, access to advanced TB diagnostics, treatments, and preventive measures remains limited for many children globally.

Purpose of the Study:

  • To conduct a comprehensive literature review on pediatric tuberculosis (TB).
  • To explore advancements in TB diagnosis, treatment (including novel drugs and regimens), and prevention of drug-resistant TB (DR-TB).
  • To identify strategies for optimizing outcomes in pediatric TB cases.

Main Methods:

  • A systematic literature search was performed using PubMed and Ovid databases.
  • The review covered publications from January 1, 1996, to October 31, 2018.
  • Key areas examined included diagnosis, treatment, prevention, and supportive care for pediatric TB.

Main Results:

  • The review synthesized current knowledge on pediatric TB management.
  • Identified innovations in diagnostics and therapeutics for TB in children.
  • Highlighted challenges in accessing these advancements for vulnerable populations.

Conclusions:

  • Significant potential exists for transformative changes in pediatric TB diagnosis, treatment, and prevention.
  • Sustained advocacy, funding, and accountability are crucial for progress.
  • Eliminating childhood TB within the next ten years is an achievable goal with concerted efforts.
Abstract

Keywords:
Tuberculosischildrendiagnosispreventiontreatment

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