Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Energy Carried By Electromagnetic Waves01:22

Energy Carried By Electromagnetic Waves

3.8K
Anyone who has used a microwave oven knows there is energy in electromagnetic waves. Sometimes, this energy is obvious, such as in the summer sun's warmth. At other times, it is subtle, such as the unfelt energy of gamma rays, which can destroy living cells. Electromagnetic waves bring energy into a system through their electric and magnetic fields. These fields can exert forces and move charges in the system and, thus, do work on them. However, there is energy in an electromagnetic wave,...
3.8K
Magnetic Force On A Current-Carrying Conductor01:25

Magnetic Force On A Current-Carrying Conductor

5.1K
Moving charges experience a force in a magnetic field. Since the magnetic fields produced by moving charges are proportional to the current, a conductor carrying a current creates a magnetic field around it.
Consider a compass placed near a current-carrying wire. The wire experiences a force that aligns the needle of the compass tangentially around the wire. Thus, the current-carrying wire produces concentric circular loops of magnetic field. The magnetic field generated by a wire can be...
5.1K
Magnetic Force On Current-Carrying Wires: Example01:22

Magnetic Force On Current-Carrying Wires: Example

2.2K
In a magnetic field, moving charges encounter a force. If a wire contains these moving charges, i.e., if the wire is carrying a current, then a force acts on the wire as well. Consider a pair of flexible leads holding a wire that is 40 cm long and 10 g in weight in a horizontal position. The wire is placed in a constant magnetic field of 0.40 T, as shown in Figure 1(a). Determine the magnitude and direction of the current flowing in the wire needed to remove the tension in the supporting leads.
2.2K
Bioequivalence Experimental Study Designs: Repeated Measures, Cross-Over, Carry-Over, and Latin Square Designs01:15

Bioequivalence Experimental Study Designs: Repeated Measures, Cross-Over, Carry-Over, and Latin Square Designs

202
Body:Bioequivalence experimental study designs play a pivotal role in testing the effectiveness of various treatments. Key among these are the repeated measures, cross-over, carry-over, and Latin square designs. In the repeated measures design, each subject receives all treatments, allowing for temporal comparisons. This type of design is useful in reducing variability but requires careful planning to avoid bias.The cross-over design, an economical method, involves sequential administration of...
202
Termination of Translation01:44

Termination of Translation

27.7K
The large ribosomal subunit has several important structures essential to translation. These include the peptidyl transferase center (PTC) - which is the site where the peptide bond is formed - and a large, internal, water-filled tube through which the nascent polypeptide moves. This latter structure is called the Peptide Exit Tunnel, and it begins at the PTC and spans the body of the large ribosomal subunit. During translation, as the nascent polypeptide chain is synthesized, it passes through...
27.7K
Protein Complex Assembly02:41

Protein Complex Assembly

16.7K
Proteins can form homomeric complexes with another unit of the same protein or heteromeric complexes with different types.  Most protein complexes self-assemble spontaneously via ordered pathways, while some proteins need assembly factors that guide their proper assembly. Despite the crowded intracellular environment, proteins usually interact with their correct partners and form functional complexes.
Many viruses self-assemble into a fully functional unit using the infected host cell to...
16.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Synthesis of All-Peptide-Based Rotaxane from a Proline-Containing Cyclic Peptide.

Biomacromolecules·2024
Same author

Reversible transformation of peptide assembly between densified-polysarcosine-driven kinetically and helix-orientation-driven thermodynamically stable morphologies.

Biomaterials science·2023
Same author

Anticoagulation Therapy for Pregnancy-Associated Thrombosis: A Retrospective Observational Study.

Annals of vascular diseases·2023
Same author

Novel Self-Forming Nanosized DDS Particles for BNCT: Utilizing A Hydrophobic Boron Cluster and Its Molecular Glue Effect.

Cells·2022
Same author

Chiral and random arrangements of flavin chromophores along cyclic peptide nanotubes on gold influencing differently on surface potential and piezoelectricity.

RSC advances·2022
Same author

Engineering pH-responsive switching of donor-π-acceptor chromophore alignments along a peptide nanotube scaffold.

RSC advances·2022

Related Experiment Video

Updated: Jan 30, 2026

Synthesis and Characterization of Amphiphilic Gold Nanoparticles
10:09

Synthesis and Characterization of Amphiphilic Gold Nanoparticles

Published on: July 2, 2019

18.2K

Joining Nanotubes Comprising Nucleobase-carrying Amphiphilic Polypeptides.

Toru Itagaki1, Yuna Ueda1, Kenji Itabashi2

  • 1Department of Material Chemistry Graduate School of Engineering, Kyoto University Kyoto-Daigaku-Katsura, Nishikyo-ku Kyoto 615-8510, Japan.

Chimia
|January 17, 2019
PubMed
Summary

Amphiphilic polypeptides self-assembled into nanotubes. Adenine-terminated nanotubes showed enhanced length extension and stability, forming strong adenine-adenine interactions and increased membrane elasticity.

More Related Videos

Engineering Molecular Recognition with Bio-mimetic Polymers on Single Walled Carbon Nanotubes
09:28

Engineering Molecular Recognition with Bio-mimetic Polymers on Single Walled Carbon Nanotubes

Published on: January 10, 2017

8.5K
Synthesis of Monocyte-targeting Peptide Amphiphile Micelles for Imaging of Atherosclerosis
08:01

Synthesis of Monocyte-targeting Peptide Amphiphile Micelles for Imaging of Atherosclerosis

Published on: November 17, 2017

7.7K

Related Experiment Videos

Last Updated: Jan 30, 2026

Synthesis and Characterization of Amphiphilic Gold Nanoparticles
10:09

Synthesis and Characterization of Amphiphilic Gold Nanoparticles

Published on: July 2, 2019

18.2K
Engineering Molecular Recognition with Bio-mimetic Polymers on Single Walled Carbon Nanotubes
09:28

Engineering Molecular Recognition with Bio-mimetic Polymers on Single Walled Carbon Nanotubes

Published on: January 10, 2017

8.5K
Synthesis of Monocyte-targeting Peptide Amphiphile Micelles for Imaging of Atherosclerosis
08:01

Synthesis of Monocyte-targeting Peptide Amphiphile Micelles for Imaging of Atherosclerosis

Published on: November 17, 2017

7.7K

Area of Science:

  • Supramolecular Chemistry
  • Materials Science
  • Biotechnology

Background:

  • Amphiphilic polypeptides are key building blocks for self-assembled nanostructures.
  • Controlling nanotube morphology and properties is crucial for advanced applications.
  • N-terminal functionalization offers a strategy to tune self-assembly behavior.

Purpose of the Study:

  • To synthesize and characterize amphiphilic polypeptides with distinct N-terminal groups.
  • To investigate the self-assembly into nanotubes and subsequent length extension.
  • To explore the role of N-terminal interactions and metal chelation in nanotube stabilization and properties.

Main Methods:

  • Synthesis of three N-terminal functionalized poly(sarcosine)-b-(L-Leu-Aib) polypeptides.
  • Self-assembly in tris buffer to form nanotubes.
  • Length extension via trifluoroethanol treatment and heat.
  • Characterization using Atomic Force Microscopy (AFM) in liquid.

Main Results:

  • Nanotubes were successfully formed from all three polypeptide types.
  • Length extension rate varied with N-terminus: adenine > glycolic acid > thymine.
  • Adenine-terminated nanotubes exhibited stronger adenine-adenine interactions, enhanced Cu(II) chelation, and increased membrane elasticity (approx. 1 MPa).

Conclusions:

  • N-terminal chromophores significantly influence polypeptide nanotube formation and properties.
  • Adenine-adenine interactions and Cu(II) chelation contribute to nanotube stabilization and mechanical strength.
  • These functionalized nanotubes hold potential for applications requiring robust nanostructures.