Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Dementia01:30

Dementia

574
Dementia is a collective term for cognitive disorders primarily affecting memory, thinking, and reasoning. It is not a specific disease but a syndrome, with Alzheimer's disease being the most common cause, accounting for approximately 60-80% of cases. Other types include vascular dementia, Lewy body dementia, and frontotemporal dementia. Dementia affects millions worldwide, particularly older adults, though it is not a normal part of aging.
The progression of dementia is generally gradual....
574
Genome-wide Association Studies-GWAS01:11

Genome-wide Association Studies-GWAS

15.7K
Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...
15.7K
What is Population Genetics?01:25

What is Population Genetics?

64.7K
A population is composed of members of the same species that simultaneously live and interact in the same area. When individuals in a population breed, they pass down their genes to their offspring. Many of these genes are polymorphic, meaning that they occur in multiple variants. Such variations of a gene are referred to as alleles. The collective set of all the alleles within a population is known as the gene pool.
64.7K
Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches01:23

Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches

467
Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
467
What are Populations and Communities?00:30

What are Populations and Communities?

37.7K
Overview
37.7K
Conservation of Small Populations02:04

Conservation of Small Populations

17.2K
Small population sizes put a species at extreme risk of extinction due to a lack of variation, and a consequent decrease in adaptability. This weakens the chances of survival under pressures such as climate change, competition from other species, or new diseases. Large populations are more likely to survive pressures such as these, as such populations are more likely to harbor individuals that have genetic variants that are adaptive under new stresses. Small populations are much less...
17.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Uncovering hidden Ī²-adrenergic agonist exposure from meat consumption through nationally representative human biomonitoring in Taiwan.

International journal of hygiene and environmental healthĀ·2026
Same author

Aristolochic acid and the risk of female lung cancer: Population-based case-control study in Taiwan.

Cancer epidemiologyĀ·2026
Same author

Role of one-carbon metabolism variants in the associations between perfluoroalkyl substances exposure and birth size in the Taiwan Birth Panel Study.

Environmental epidemiology (Philadelphia, Pa.)Ā·2026
Same author

REAL-WORLD PRACTICE OF ARTIFICIAL INTELLIGENCE DIAGNOSTIC SYSTEM FOR DIABETIC RETINOPATHY IN TAIWAN.

Retina (Philadelphia, Pa.)Ā·2026
Same author

Early-childhood exposure to per- and polyfluoroalkyl substances (PFAS) and neurobehavioral development in children.

Environmental researchĀ·2026
Same author

Associations between prenatal metal exposure, gene variants, and birth size in Taiwan Birth Panel Study.

Pediatric researchĀ·2026
Same journal

Circulating Tumor DNA as a Biomarker for Melanoma Prognosis and Therapy.

American journal of clinical dermatologyĀ·2026
Same journal

Defining the Potential for Disease Modification in Atopic Dermatitis.

American journal of clinical dermatologyĀ·2026
Same journal

Atopic Dermatitis: New Targets and Emerging Systemic Therapies.

American journal of clinical dermatologyĀ·2026
Same journal

Rethinking Head and Neck Atopic Dermatitis: Pathogenic Axes and Emerging Therapeutic Directions.

American journal of clinical dermatologyĀ·2026
Same journal

Correction: Integrated Safety Analysis of Ritlecitinib, an Oral JAK3/TEC Family Kinase Inhibitor, for the Treatment of Alopecia Areata from the ALLEGRO Clinical Trial Program.

American journal of clinical dermatologyĀ·2026
Same journal

A Systematic Review of the Clinical Impact of GLP-1 Receptor Agonists in Hidradenitis Suppurativa.

American journal of clinical dermatologyĀ·2026
See all related articles

Related Experiment Video

Updated: Jan 30, 2026

Using Retinal Imaging to Study Dementia
09:17

Using Retinal Imaging to Study Dementia

Published on: November 6, 2017

22.3K

Association Between Psoriasis and Dementia: A Population-Based Case-Control Study.

Ching-Chun Lin1, Herng-Ching Lin2, Hung-Wen Chiu3

  • 1Graduate Institute of Biomedical Informatics, College of Medicine Science and Technology, Taipei Medical University, 250 Wu-Hsing St., Taipei, 110, Taiwan.

American Journal of Clinical Dermatology
|January 17, 2019
PubMed
Summary
This summary is machine-generated.

Individuals with dementia were more likely to have a prior diagnosis of psoriasis. This population-based study in Taiwan suggests a potential link between psoriasis and dementia risk, warranting further investigation.

More Related Videos

Author Spotlight: Self-Assessment Protocol for Predicting Psoriatic Arthritis in Psoriasis Patients
02:28

Author Spotlight: Self-Assessment Protocol for Predicting Psoriatic Arthritis in Psoriasis Patients

Published on: March 1, 2024

933
The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
11:39

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis

Published on: July 11, 2013

39.5K

Related Experiment Videos

Last Updated: Jan 30, 2026

Using Retinal Imaging to Study Dementia
09:17

Using Retinal Imaging to Study Dementia

Published on: November 6, 2017

22.3K
Author Spotlight: Self-Assessment Protocol for Predicting Psoriatic Arthritis in Psoriasis Patients
02:28

Author Spotlight: Self-Assessment Protocol for Predicting Psoriatic Arthritis in Psoriasis Patients

Published on: March 1, 2024

933
The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
11:39

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis

Published on: July 11, 2013

39.5K

Area of Science:

  • Neurology
  • Dermatology
  • Epidemiology

Background:

  • Dementia is a syndrome of cognitive decline in older adults.
  • Psoriasis is an autoimmune skin condition.
  • Previous studies suggest an association between dementia and psoriasis, but Asian data is lacking.

Purpose of the Study:

  • To investigate the association between a prior diagnosis of psoriasis and dementia in Taiwan.
  • Utilize a population-based medical dataset for robust analysis.

Main Methods:

  • A cohort of 7,118 dementia patients and 21,354 matched controls from the Taiwan Longitudinal Health Insurance Database 2000.
  • Conditional logistic regression analysis adjusted for comorbidities and socioeconomic factors.
  • Bullous pemphigoid patients served as a control for inflammatory conditions.

Main Results:

  • A higher prevalence of psoriasis was observed in the dementia group (3.0%) compared to the control group (1.5%).
  • Individuals with dementia had a significantly higher odds ratio (OR) for prior psoriasis (OR = 1.46, 95% CI 1.23-1.73).
  • Psoriasis with arthritis showed a stronger association with dementia (OR = 1.95) than psoriasis without arthritis (OR = 1.44).

Conclusions:

  • The study found a significant association between a prior diagnosis of psoriasis and dementia in the Taiwanese population.
  • No significant association was found between bullous pemphigoid and dementia.
  • Further research is needed to confirm these findings and elucidate the underlying mechanisms linking psoriasis and dementia.