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Relationship between primary open angle glaucoma and blood pressure.

Kerem Can Yilmaz1, Sirel Sur Gungor2, Orcun Ciftci1

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Acta Cardiologica
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Summary

Glaucoma patients often experience lower blood pressure, particularly at night. Monitoring blood pressure variability is crucial for managing glaucoma progression and considering treatment adjustments.

Keywords:
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Area of Science:

  • Ophthalmology
  • Cardiology
  • Nephrology

Background:

  • Glaucoma is characterized by high intraocular pressure and optic nerve damage.
  • Primary open-angle glaucoma (POAG) has been linked to systemic hypertension and hypotension.
  • Understanding blood pressure variability in glaucoma patients is essential.

Purpose of the Study:

  • To compare 24-hour ambulatory blood pressure variability in glaucoma patients versus controls.
  • To identify potential associations between blood pressure patterns and glaucoma.

Main Methods:

  • A study included 75 participants: 35 with glaucoma and 40 controls.
  • Ambulatory blood pressure monitoring was used to record daytime, nighttime, and whole-day BP.
  • Data were analyzed to compare blood pressure readings between groups.

Main Results:

  • Glaucoma patients showed significantly lower mean daytime systolic BP compared to controls.
  • Night-time systolic BP, whole-day systolic BP, and mean diastolic BP were also significantly lower in glaucoma patients.
  • Daytime, night-time, and whole-day systolic BP were identified as independent risk factors for glaucoma.

Conclusions:

  • Night-time hypotension should be investigated in glaucoma patients with disease progression.
  • Reviewing and adjusting medications may be necessary if night-time hypotension is detected.
  • Ambulatory blood pressure monitoring is recommended for glaucoma management.