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In vitro influence of charcoal on ciprofloxacin activity
D Torre1, C Sampietro, C Quadrelli
1Division of Infectious Diseases, General Hospital, Varese, Italy.
Drugs Under Experimental and Clinical Research
|January 1, 1988
Abstract:
The effect of charcoal-containing media on ciprofloxacin (BAY o 9867) has been evaluated. The minimal inhibitory concentrations of ciprofloxacin are increased by the presence of charcoal, thus a correction factor has to be calculated to know the real efficacy of the drug, especially in life-threatening infections such as pneumonia due to Legionella spp.