Related Experiment Video
Updated: Jan 30, 2026

Vein Interposition Model: A Suitable Model to Study Bypass Graft Patency
Published on: January 15, 2017
Long-term graft patency after coronary artery bypass grafting: Effects of surgical technique
Grigore Tinica1,2, Raluca Ozana Chistol3, Diana Bulgaru Iliescu4,5
1Department of Cardiovascular Surgery, 'Prof. Dr. George I.M. Georgescu' Cardiovascular Diseases Institute, 700503 Iasi, Romania.
Insights
Surgical factors like anastomosis angles significantly impact long-term graft patency after coronary artery bypass grafting (CABG). Smaller angles in proximal Y and distal anastomoses improve graft survival, especially for arterial grafts.
Area of Science:
- Cardiovascular Surgery
- Vascular Grafting
- Surgical Technique Optimization
Background:
- Long-term patency of grafts is crucial for coronary artery bypass grafting (CABG) success.
- Identifying surgical factors influencing graft longevity remains an important clinical goal.
Purpose of the Study:
- To identify surgical factors associated with long-term graft patency in patients undergoing coronary artery bypass grafting (CABG).
Main Methods:
- Analysis of data from 127 patients who underwent CABG between 2000-2006.
- Coronary computed tomography angiography was used to evaluate graft patency at a mean of 139.78 months post-CABG.
- Assessment of graft patency in relation to anastomosis types and angles.
Main Results:
- Graft patency varied by coronary territory, proximal anastomosis type, and Y/distal anastomosis angles.
- A single end-to-side anastomosis angle ≥60° was linked to a 5.149 odds ratio for occlusion in arterial grafts.
- Radial artery grafts showed higher patency when anastomosed to the ascending aorta versus composite grafting.
Conclusions:
- Smaller anastomosis angles in proximal Y and distal anastomoses are associated with higher long-term patency for free grafts.
- Specific arterial graft strategies, like radial artery to ascending aorta anastomosis, improve patency.
- In situ right internal thoracic artery grafting to the right coronary territory showed lower patency compared to other composite grafting scenarios.
Abstract:
The aim of the current study was to identify surgical factors associated with long-term patency of grafts used in coronary artery bypass grafting (CABG). The present study analyzed data from 127 patients who underwent CABG at our institute between 2000 and 2006 and presented for ambulatory examination and coronary computed tomography angiography evaluation of graft patency in 2016 (139.78±36.64 months post-CABG). The 127 patients received 340 grafts (2.68 grafts/patient) and 399 distal anastomoses (3.14 anastomoses/patient), 220 (55.14%) with arterial grafts and 179 (44.86%) with saphenous vein grafts. Graft patency varied according to coronary territory, proximal anastomosis type (in situ graft, composite graft, graft anastomosed to the ascending aorta), Y anastomosis angle (47.21° for patent arterial grafts vs. 56° for occluded), and distal anastomosis angle (in sequential anastomoses irrespective to graft type, 48.60° for patent side-to-side anastomosis vs. 53.97° for occluded, 65.12° for patent end-to-side anastomosis vs. 90.80° for occluded; in single end-to-side anastomosis of arterial grafts, 39.46° for patent and 44.94° for occluded). A single end-to-side anastomosis angle 60° or greater was associated with a 5.149 occlusion odds ratio (OR) (P<0.001) for arterial grafts. Venous grafts were not sensitive to single end-to-side anastomosis angle. In conclusion, a small anastomosis angle for proximal Y and distal anastomoses is associated with a higher long-term patency of the free graft. Radial artery grafts registered higher patency rates when anastomosed to the ascending aorta compared with composite grafting with the left internal thoracic artery, whereas in situ right internal thoracic artery (RITA) anastomosed to the right coronary territory is associated with a lower patency rate compared with free RITA used to revascularise the anterolateral or circumflex territory in composite grafting.
Related Concept Videos
Coronary Artery Disease I: Introduction
Coronary Artery Disease II: Pathophysiology
Coronary Artery Disease V: Interprofessional Care
Coronary Artery Disease III: Clinical Manifestations
Coronary Artery Disease IV: Preventive Measures
Long-term Depression

