Extradural cervical spinal meningioma mimicking malignancy

Area of Science:

• Neurosurgery
• Spinal Oncology
• Neuropathology

Background:

• Intraspinal meningiomas are typically intradural and extramedullary.
• Extradural meningiomas are rare, particularly in the cervical spine.
• Extradural meningiomas can exhibit aggressive behavior and mimic malignant tumors.

Observation:

• This report details an exceptional case of a purely extradural meningioma in the cervical spine.
• The tumor demonstrated multi-segmental involvement and extended through neural foramina.
• It encased the subjacent vertebral artery, presenting a diagnostic challenge.

Findings:

• The invasive extradural meningioma showed features often associated with malignancy.
• The lesion mimicked other neoplasms like lymphoma and sarcoma.
• This case underscores the potential for extradural meningiomas to present with aggressive, multi-segmental growth.

Implications:

• Extradural meningiomas, though rare, must be included in the differential diagnosis of cervical spine lesions with aggressive features.
• Accurate diagnosis is crucial for appropriate treatment planning and patient management.
• Further research into the biological behavior of extradural meningiomas may improve diagnostic and therapeutic strategies.