Related Experiment Video
Updated: Jan 30, 2026

Multiple-mouse Neuroanatomical Magnetic Resonance Imaging
Published on: February 27, 2011
The diaphragma sellae, diaphragm opening, and subdiaphragmatic cistern: an anatomical study using magnetic resonance
Satoshi Tsutsumi1, Hideo Ono2, Yukimasa Yasumoto3
1Department of Neurological Surgery, Juntendo University Urayasu Hospital, 2-1-1 Tomioka, Urayasu, 279-0021, Chiba, Japan. shotaro@juntendo-urayasu.jp.
Purpose:
Few studies have explored the detailed morphology of the diaphragma sellae (DS), diaphragm opening (DO) or stoma, and subdiaphragmatic cistern (SDC) using neuroimages. The aim of the present study was to characterize these structures using magnetic resonance imaging.
Methods:
Thin-sliced, sagittal and coronal T2-weighted imaging was performed for a total of 84 outpatients.
Results:
The DS, DO, SDC, and relevant structures were consistently delineated in all patients. In 66% of patients, all three structures appeared to be highly variable, and were classifiable as six distinct morphological types. In 4% of patients, the DS presented as a complete sheet lacking a discernible DO. In addition, 30% of the patients presented with undiscernible SDCs. In the coronal sections of 11% of patients, the pituitary glands extended laterally, reaching or extending beyond the center line on the sectional image of the cavernous internal carotid artery.
Conclusions:
Thin-sliced, sagittal, and coronal T2-weighted sequences are useful for delineating the DS, DO, and SDC. Morphological variation of these structures among individuals may considerably influence the direction of pituitary tumor expansion.
Related Concept Videos
Imaging Studies IV: Magnetic Resonance Imaging
Magnetic Resonance Imaging
Atomic Nuclei: Magnetic Resonance
Nuclear Magnetic Resonance (NMR): Overview
NMR spectroscopy generates a spectrum where the characteristic absorption frequencies of the sample are...
Resonance
Anatomical Positions
The body is upright, facing forward, and standing erect.
The feet are parallel and flat on the floor.
The arms are hanging by the...

