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Ocular abnormalities in morbid obesity.

Kuddusi Teberik1, M Tahir Eski2, Sami Doğan3

  • 1Department of Ophthalmology, Faculty of Medicine, Duzce University, Duzce, Turkey.

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Summary
This summary is machine-generated.

Morbid obesity is linked to higher intraocular pressure and reduced retinal and choroidal thickness, suggesting increased risks for glaucoma and optic neuropathy. These findings highlight the ocular structural changes associated with severe obesity.

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Area of Science:

  • Ophthalmology
  • Metabolic Disorders
  • Medical Imaging

Background:

  • Obesity is a growing global health concern.
  • Emerging evidence suggests a link between obesity and various eye diseases.
  • However, detailed examination of structural changes and pathogenic mechanisms in morbid obesity is lacking.

Purpose of the Study:

  • To investigate the effects of morbid obesity on morphometric indices of eye disease.
  • To compare ocular structural parameters between morbidly obese individuals and healthy controls.

Main Methods:

  • Study included 101 morbidly obese volunteers (BMI ≥ 40) and 95 healthy controls (BMI 18.50–24.99).
  • Ocular parameters were assessed using Goldman applanation tonometry, pachymetry, and spectral domain optical coherence tomography.
  • Measurements included intraocular pressure, anterior chamber depth, axial length, central corneal thickness, retinal nerve fiber layer thickness, central foveal thickness, and choroidal thickness.

Main Results:

  • Morbidly obese individuals exhibited significantly greater uncorrected intraocular pressure compared to controls.
  • Retinal nerve fiber layer thickness and mean retinal thicknesses were reduced in the morbidly obese group.
  • Choroidal thickness was also reduced in most measurement locations, with negative correlations between weight/BMI and subfoveal choroidal thickness.

Conclusions:

  • Morbid obesity is associated with elevated intraocular pressure and signs of neuropathy and retinopathy.
  • These ocular changes may increase the risk of developing glaucoma and glaucomatous optic neuropathy.
  • The study underscores the importance of considering ocular health in the context of severe obesity.