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ERCP in infants, children, and adolescents-Different roles of the methods in different age groups
Radan Keil1, Jiří Drábek1, Jindra Lochmannová1
1Department of Internal Medicine, Charles University, 2nd Faculty of Medicine, University Hospital Motol, Prague, Czech Republic.
Insights
Endoscopic retrograde cholangiopancreatography (ERCP) is safe and effective in children, with success rates similar to adults. This large pediatric study highlights ERCP
Area of Science:
- Pediatric Gastroenterology
- Endoscopic Procedures
- Biliopancreatic Disorders
Background:
- Endoscopic retrograde cholangiopancreatography (ERCP) is infrequently utilized in pediatric populations.
- Existing published series often lack substantial numbers of pediatric patients.
Purpose of the Study:
- To evaluate the efficacy and safety of pediatric ERCP.
- To assess outcomes in a large cohort of children undergoing ERCP.
Main Methods:
- Retrospective observational study design.
- Analysis of data from 626 pediatric patients with biliopancreatic disorders.
- Review of clinical records and a database of ERCP procedures.
Main Results:
- 856 ERCP procedures were performed on 626 children, with 59% therapeutic and 41% diagnostic.
- Achieved a 96% technical success rate.
- Identified age-specific indications and findings, including biliary atresia exclusion in infants and choledocholithiasis in older children.
Conclusions:
- Pediatric ERCP demonstrates comparable efficacy and safety to adult procedures.
- ERCP plays a crucial role in diagnosing and treating biliopancreatic disorders across different pediatric age groups.
Background:
Endoscopic retrograde cholangiopancreatography (ERCP) is seldom used in children, and published series have limited numbers of pediatric patients. The aim of this retrospective observational study was to assess the efficacy and safety of pediatric ERCP in a large group of children.
Methods:
Data were evaluated from 626 children with biliopancreatic disorders admitted to University Hospital Motol, Prague, between January 1999 and January 2018. Clinical data were obtained by retrospective evaluation of our database of pediatric ERCP procedures and from clinical records.
Results:
We performed 856 ERCPs on 626 pediatric patients; of these procedures, 59% were therapeutic and 41% were diagnostic. We achieved 96% technical success. Indications for ERCP and pathological findings differed in different age groups. The main role of ERCP was in excluding biliary atresia in those aged less than one year. In children aged 1 to 6 years, the most frequent diagnoses were choledochal cyst followed by choledocholithiasis. In children aged 7 to 12 years and 13 to 19 years, the most frequent diagnoses were choledocholithiasis followed by pancreatic pathology. The overall complication rate found in this study was similar to rates observed in adult populations.
Conclusions:
Our study shows the efficacy and safety of diagnostic and therapeutic ERCP in a large series of infants and children with technical success and complication rates comparable to those in adults. Our data show that ERCP had different roles in different age groups of children.
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