ERCP in infants, children, and adolescents-Different roles of the methods in different age groups

Radan Keil1, Jiří Drábek1, Jindra Lochmannová1

  • 1Department of Internal Medicine, Charles University, 2nd Faculty of Medicine, University Hospital Motol, Prague, Czech Republic.

Plos One
|January 18, 2019
PubMed

Insights

Endoscopic retrograde cholangiopancreatography (ERCP) is safe and effective in children, with success rates similar to adults. This large pediatric study highlights ERCP

Area of Science:

  • Pediatric Gastroenterology
  • Endoscopic Procedures
  • Biliopancreatic Disorders

Background:

  • Endoscopic retrograde cholangiopancreatography (ERCP) is infrequently utilized in pediatric populations.
  • Existing published series often lack substantial numbers of pediatric patients.

Purpose of the Study:

  • To evaluate the efficacy and safety of pediatric ERCP.
  • To assess outcomes in a large cohort of children undergoing ERCP.

Main Methods:

  • Retrospective observational study design.
  • Analysis of data from 626 pediatric patients with biliopancreatic disorders.
  • Review of clinical records and a database of ERCP procedures.

Main Results:

  • 856 ERCP procedures were performed on 626 children, with 59% therapeutic and 41% diagnostic.
  • Achieved a 96% technical success rate.
  • Identified age-specific indications and findings, including biliary atresia exclusion in infants and choledocholithiasis in older children.

Conclusions:

  • Pediatric ERCP demonstrates comparable efficacy and safety to adult procedures.
  • ERCP plays a crucial role in diagnosing and treating biliopancreatic disorders across different pediatric age groups.
Abstract

Related Concept Videos

Drug Dosing: Infants and Children01:29

Drug Dosing: Infants and Children

Pediatric patient dosages diverge from adults due to disparities in body surface area, total body water, and extracellular fluid per kilogram of body weight. The dosing regimen considers the variations in pharmacokinetics and pharmacology across distinct age groups, encompassing preterm newborns, infants, young children, older children, and adolescents. Calculation of pediatric patient doses is predicated on determining body surface area, which exhibits a superior correlation with the child's...
293
Endoscopic Procedures V: ERCP01:26

Endoscopic Procedures V: ERCP

Endoscopic Retrograde Cholangiopancreatography (ERCP) is a diagnostic procedure that combines endoscopy and fluoroscopy to diagnose and treat conditions related to the bile ducts, pancreatic ducts, and gallbladder. This procedure is beneficial for identifying and addressing blockages, gallstones, strictures, and tumors within the biliary or pancreatic systems. ERCP is both diagnostic and therapeutic, offering the ability to visualize and treat identified problems in one session.
Patient...
3.3K
Cognitive Development During Adolescence01:18

Cognitive Development During Adolescence

During adolescence, individuals experience significant cognitive development that enhances their understanding of others' emotions and thoughts, known as cognitive empathy. This period is marked by an increased ability to adapt to others' perspectives and a more nuanced understanding of others' mental states, a skill that is foundational for social problem-solving and conflict avoidance. The development of cognitive empathy relies heavily on the theory of mind — the...
597
Aging01:26

Aging

Aging is a complex biological phenomenon influenced by various processes that affect cellular and systemic functions. Several prominent theories attempt to explain its mechanisms, highlighting cellular limitations, oxidative damage, and hormonal changes as central factors in aging.
Cellular Clock Theory
The cellular clock theory posits that the human lifespan is closely tied to the finite capacity of cells to divide, a phenomenon governed by telomeres, which are protective caps at the ends of...
698
Erikson's Theory on Socioemotional Development during Adolescence01:17

Erikson's Theory on Socioemotional Development during Adolescence

Erik Erikson's fifth stage of psychosocial development, "identity versus role confusion," is crucial during adolescence (ages 12 to 18). In this stage, adolescents face the developmental task of forging a distinct personal identity, a process influenced by social, psychological, and biological changes typical of this period. Adolescents naturally explore different roles, behaviors, and ideologies as they navigate complex questions of self-concept, asking, "Who am I?" and "What is my place in...
1.2K
Revisionist Views of Adolescent and Adult Cognition01:24

Revisionist Views of Adolescent and Adult Cognition

A revisionist approach to Jean Piaget's theory of cognitive development has brought new insights that challenge and reinterpret his established ideas. Piaget proposed that the formal operational stage, emerging in adolescence, represents the culmination of cognitive maturity. During this stage, individuals are said to develop abstract thinking, engage in systematic problem-solving, and show a form of egocentrism, believing others are as preoccupied with their behavior as they are...
303