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Acute dystonic reaction due to diazepam.

E A Hooker1, D F Danzl

  • 1Department of Emergency Medicine, University of Louisville, KY 40292.

The Journal of Emergency Medicine
|November 1, 1988
PubMed
Summary

Acute dystonic reactions, a type of extra-pyramidal syndrome, can occur after diazepam ingestion. Intravenous diphenhydramine effectively treated these reactions in two reported cases.

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Area of Science:

  • Neurology
  • Pharmacology
  • Toxicology

Background:

  • Drug-induced extra-pyramidal syndromes are a recognized class of adverse drug reactions.
  • Benzodiazepines, including diazepam, are commonly prescribed for anxiety and sedation.
  • Dystonic reactions are characterized by involuntary muscle contractions.