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Related Concept Videos

Sign Convention01:30

Sign Convention

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When analyzing a beam subjected to various loads, it is crucial to understand the internal forces and moments generated within the structure. These internal forces can be broadly classified into normal forces, shear forces, and bending moments. To determine these forces and moments, we use the method of sections and apply a specific sign convention based on their direction and the side of the section being analyzed.
The normal force acts perpendicular to the beam's cross-section and can...
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Signs of Puberty01:27

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Puberty is a critical phase, typically beginning between the ages of 8 and 13 in girls and 9 and 14 in boys, though timing can vary based on genetics, environmental factors, and overall health. This period is characterized by the development of secondary sexual characteristics and the attainment of reproductive potential. Endocrine changes underpin puberty, with hormonal surges of Luteinizing Hormone (LH) and Follicle-Stimulating Hormone (FSH) instigated by Gonadotropin-Releasing Hormone (GnRH)...
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Introduction to the Sign Test01:10

Introduction to the Sign Test

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The sign test is an important tool in nonparametric statistics, offering a straightforward yet effective method for analyzing matched pairs, nominal data, or hypotheses concerning the median of a population. It transforms data points into positive or negative signs, avoiding the need for assumptions about data distribution and instead focusing on the direction of change. It is particularly valuable when data does not conform to the normal distribution requirements of many parametric tests. For...
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Introduction to Vital Signs01:25

Introduction to Vital Signs

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Vital signs are physiological measurements that help key into the status of the body's essential functions. These include body temperature, pulse rate, respiratory rate, and blood pressure, commonly abbreviated as T, P, R, and BP. Some healthcare settings also consider oxygen saturation (SpO2) and, in specific contexts, pain and level of consciousness as additional vital signs.
Vital signs help healthcare professionals assess an individual's well-being and detect any functional changes...
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Sign Test for Nominal Data01:12

Sign Test for Nominal Data

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The sign test is a nonparametric method used to evaluate hypotheses about the median of a single sample or to compare the medians of two related samples. The sign test is particularly useful when dealing with nominal data, which includes distinct categories without an inherent order, such as names, labels, and preferences. Nominal data restricts statistical analysis to evaluating population proportions rather than mean or median values that require continuous data.
For example, consider a...
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Sign Test for Matched Pairs01:17

Sign Test for Matched Pairs

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The sign test for matched pairs offers a robust method for comparing two paired samples, often for the effects of an intervention in one of them. This method is very useful in situations where the underlying distribution of the data is unknown. The test compares two related samples—often pre- and post-treatment measurements on the same subjects—to determine if there are significant differences in their median values.
To conduct the sign test, we first calculate the differences in...
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Related Experiment Video

Updated: Jan 30, 2026

Implantation and Monitoring by PET/CT of an Orthotopic Model of Human Pleural Mesothelioma in Athymic Mice
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Lambda sign in sarcoidosis using PET/CT.

Joe Thomas1, Gopalannair Santhamma Shagos2, Ibrahim Firuz2

  • 1Department of Orthopaedics & Rheumatology Aster Medcity Kochi India.

Clinical Case Reports
|January 19, 2019
PubMed
Summary

The lambda sign aids in diagnosing sarcoidosis. Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography (FDG PET/CT) is crucial for managing chronic sarcoidosis patients.

Keywords:
PET/CTlambda signsarcoidosis

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Area of Science:

  • Medical Imaging
  • Pulmonology
  • Oncology

Background:

  • Sarcoidosis is a multisystem inflammatory disease.
  • The lambda sign is a recognized diagnostic indicator.
  • FDG PET/CT has emerged as a key imaging modality.

Purpose of the Study:

  • To highlight the diagnostic value of the lambda sign in sarcoidosis.
  • To emphasize the role of FDG PET/CT in sarcoidosis management.
  • To discuss FDG PET/CT applications in therapy planning and patient follow-up.

Main Methods:

  • Review of diagnostic criteria for sarcoidosis.
  • Analysis of FDG PET/CT utility in sarcoidosis.
  • Case studies illustrating the lambda sign and FDG PET/CT findings.

Main Results:

  • The lambda sign is a specific finding in sarcoidosis diagnosis.
  • FDG PET/CT effectively visualizes disease activity and extent.
  • FDG PET/CT guides therapeutic interventions and monitors treatment efficacy.

Conclusions:

  • The lambda sign is a valuable diagnostic marker for sarcoidosis.
  • FDG PET/CT is indispensable for comprehensive sarcoidosis patient care.
  • Integrated use of diagnostic signs and advanced imaging optimizes sarcoidosis management.