Related Experiment Video
Updated: Jan 30, 2026

Synthesis of Near-Infrared Emitting Gold Nanoclusters for Biological Applications
Published on: March 22, 2020
Reversible pH-induced fluorescence colour change of gold nanoclusters based on pH-regulated surface interactions
Daniel Cuaran-Acosta1, Pablo Londoño-Larrea, Elena Zaballos-García
1Departamento de Química Orgánica, Universidad de Valencia, Av. Vicent Andres Estelles s/n, Burjassot, 46100, Spain.
Abstract:
To prepare water-dispersible, biocompatible, ratiometric pH nanosensors is challenging. We report here for the first time that the emission colour of NAD+-capped AuNCs responds to the mono-/bidentate anchoring of the phosphoric groups of the ligand. The AuNCs exhibit a high luminescence (21% quantum yield) and an outstanding performance as fluorescent ratiometric pH sensors over a broad pH range.
Related Concept Videos
Entropy Change in Reversible Processes
The statement can be further generalized to prove that entropy is a state function. Take a cyclic process between any two points on a p-V diagram.
Global Climate Change
GTPases and their Regulation
Large G-proteins,...
Respiratory Regulation of Acid-Base Balance
When carbon dioxide levels increase in the blood, more H+ and HCO3⁻ are...
Le Chatelier's Principle: Changing Concentration
Renal Regulation of Acid-Base Balance
In the kidneys, cells within the proximal convoluted tubules (PCT) and the collecting ducts secrete hydrogen ions (H+) into the tubular fluid. Specifically, in the PCT, Na+/H+ antiporters secrete H+ while reabsorbing Na+.
However, the intercalated cells in...

