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Updated: Jan 30, 2026
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Percutaneous renal mass biopsy: historical perspective, current status, and future considerations
Brittney H Cotta1, Margaret F Meagher1, Aaron Bradshaw1
1a Department of Urology , University of California San Diego School of Medicine , La Jolla , CA , USA.
Expert Review of Anticancer Therapy
|January 19, 2019
Summary
Percutaneous renal mass biopsy is now more accurate and reliable. This minimally invasive procedure helps guide personalized treatment for kidney cancers, improving patient care.
Area of Science:
- Urology
- Nephrology
- Oncology
Background:
- Percutaneous renal mass biopsy (PRMB) has historically faced challenges like low tissue yield and high non-diagnostic rates.
- Advances in understanding renal cortical neoplasm biology and natural history are reshaping treatment paradigms.
Purpose of the Study:
- To review the evolution of PRMB, focusing on improvements in outcomes, indications, and current clinical guidelines.
- To highlight the expanding role of PRMB in individualized management and risk stratification of renal masses.
Main Methods:
- Review of recent literature on PRMB techniques and outcomes.
- Analysis of current clinical guidelines and expert opinions regarding PRMB utilization.
Main Results:
- Significant improvements in tissue yield, diagnostic accuracy, and reduced complication rates for PRMB.
- PRMB is increasingly recognized as a valuable tool for active surveillance, thermal ablation, and systemic therapy decisions.
Conclusions:
- PRMB has evolved into a more reliable diagnostic tool with improved technical performance.
- Its utilization is expanding, offering crucial information for personalized management of renal cortical neoplasms across various clinical settings.
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