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Updated: Jan 30, 2026

Author Spotlight: High-Resolution Imaging of Mouse Neonate Brains – A Micro-CT Protocol with Lugol's Solution Contrast Agent
Published on: May 19, 2023
Imaging the term neonatal brain
S Todd Sorokan1, Ann L Jefferies1, Steven P Miller1
1Canadian Paediatric Society, Fetus and Newborn Committee, Ottawa, Ontario.
Abstract:
Brain imaging is important for the diagnosis and management of sick term neonates. Although ultrasound and computed tomography may provide some information, magnetic resonance imaging is now the brain imaging modality of choice because it is the most sensitive technique for detecting and quantifying brain abnormalities and does not expose infants to radiation. This statement describes the principles, roles and limitations of these three imaging modalities and makes recommendations for appropriate use in term neonates. The primary focus is the brain of term infants with neonatal encephalopathy, many of whom are diagnosed with hypoxic-ischemic encephalopathy.
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