Gaucher's disease and pregnancy

Two patients with Gaucher's disease during pregnancy are reported. In one there were severe puerperal hemorrhagic complications attributable to thrombocytopenia secondary to infiltration of the reticuloendothelial system by Gaucher cells. The conclusion as reported in previous literature, which is reviewed, regarding the absence of hemorrhagic complications is disputed since on of the cases reported here showed that these may be severe and occur late in the puerperium.