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Updated: Jan 30, 2026

Laparoscopic Anatomical Hepatectomy Using Takasaki's Approach and Indocyanine Green Fluorescence Navigation
Published on: May 16, 2025
Efficacy of Hepatic Segmental Visualization Using Indocyanine Green Photodynamic Eye Imaging
Atsushi Nanashima1,2, Koichi Yano3, Shuichi Tobinaga4
1Division of Hepato-biliary-pancreas Surgery, Department of Surgery, University of Miyazaki Faculty of Medicine, Kiyotake 5200, Miyazaki, 889-1692, Japan. a_nanashima@med.miyazaki-u.ac.jp.
Background:
To clarify the usefulness of identification of hepatic segmentation stained with an indocyanine green-photodynamic eye (ICG-PDE) system, we sequentially investigated the matching of visualization during hepatectomy in 40 patients at two institutions between 2009 and 2017.
Methods:
A low dose of ICG was administered into the portal flow to stain the estimated segments of the liver to be resected during hepatectomy, and segmentation images were observed using a PDE camera. Intraoperative ICG-PDE could be carried out for all patients without side effects.
Results:
Complete segmental identification of the liver by blue dye stain and ICG-PDE was achieved in 30 (75%) and 35 (88%) patients, respectively, but the prevalence between them was not significantly different (p = 0.302). ICG-PDE segmentation in the estimated area was incomplete in three patients, and complete failure (no staining) was observed in two patients. The border between the posterior section and the caudate was identified in two patients.
Conclusion:
This preliminary study showed ICG-PDE to be a useful tool for clearly determining liver segmentation to estimate the area for resection.
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