A green extraction material - natural cotton fiber for in-tube solid-phase microextraction
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Updated: Jan 30, 2026

Gas Chromatography-Mass Spectrometry Paired with Total Vaporization Solid-Phase Microextraction as a Forensic Tool
Published on: May 25, 2021
Juanjuan Feng1, Sen Han1, Xiangping Ji1
1Key Laboratory of Interfacial Reaction & Sensing Analysis in Universities of Shandong, School of Chemistry and Chemical Engineering, University of Jinan, Jinan, P. R. China.
Abstract:
Natural cotton fiber was applied as a green extraction material for in-tube solid-phase microextraction. Cotton fibers were characterized by scanning electron microscope. A bundle of cotton fibers (685 mg, 20 cm) was directly packed into a polyetheretherketone tube (i.d. 0.75 mm) to get the extraction device. It was connected into high performance liquid chromatography, building an online extraction and dectection system. Through the online analysis system, several polycyclic aromatic hydrocarbons were used as the targets to evaluate the extraction performace of the device. In order to get high extraction efficiency and sensitivity, the extraction and desorption conditions were optimized. Under the optimum conditions, the sensitive analysis method was established, and provided low limits of detection of 0.02 and 0.05 μg/L, good linearity ranges of 0.06-15 and 0.16-15 μg/L, as well as high enrichment factors of 176-1868. The method was applied to the online determination of trace polycyclic aromatic hydrocarbons in snow water and river water, and the relative recoveries corresponding to 2 and 5 μg/L were in the range of 80-116%. The repeatability of extraction and preparation of the device was investigated and the relative standard deviations (n = 3) were less than 3.6 and 5.2%.
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