Related Experiment Video
Updated: Jan 30, 2026
07:49
Measuring Local Anaphylaxis in Mice
Published on: October 14, 2014
20.0K
Anaphylaxis to Beluga caviar
Sébastien Lefèvre1, Laurianne Moumane2, Sandrine Jacquenet3
1Allergy department, Metz Regional Hospital, 1 allée du Château, 57530 Ars-Laquenexy, France.
Asian Pacific Journal of Allergy and Immunology
|January 21, 2019
Summary
Fish roe, specifically caviar, can cause rare anaphylaxis. This case highlights a 59-year-old man
Area of Science:
- Allergy and Immunology
- Food Hypersensitivity
- Clinical Case Study
Background:
- Fish roe consumption is increasing globally.
- Anaphylaxis to fish roe is exceptionally rare in medical literature.
- Accurate diagnosis of food-induced anaphylaxis requires careful allergen identification.
Observation:
- A 59-year-old male presented with anaphylaxis post-caviar ingestion.
- Skin prick testing (SPT) was positive exclusively to Beluga caviar.
- Specific IgE testing showed no sensitization to common fish or hen egg allergens.
Findings:
- Immunoblotting identified a specific IgE-binding protein at 26 kDa in Beluga caviar.
- This 26 kDa protein appears novel, as it does not match previously reported fish roe allergens.
- The patient demonstrated specific sensitization to this unique caviar protein.
Implications:
- This case expands the understanding of fish roe as a potential anaphylaxis trigger.
- Highlights the importance of immunoblotting for identifying specific allergens in rare food allergies.
- Suggests the existence of novel allergens within fish roe, necessitating further research.
